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Eliane Namie Miyaji et al.
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Mucosal Immunization with an Unadjuvanted Vaccine That Targets Streptococcus pneumoniae PspA to Human Fcγ Receptor Type I Protects against Pneumococcal Infection through Complement- and Lactoferrin-Mediated Bactericidal Activity
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Impact of More Than a Decade of Pneumococcal Conjugate Vaccine Use on Carriage and Invasive Potential in Native American Communities
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CELL HOST & MICROBE (2011)
Serine Protease PrtA from Streptococcus pneumoniae Plays a Role in the Killing of S. pneumoniae by Apolactoferrin
Shaper Mirza et al.
INFECTION AND IMMUNITY (2011)
Serotype replacement in disease after pneumococcal vaccination
Daniel M. Weinberger et al.
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The effect of age on the response to the pneumococcal polysaccharide vaccine
Hyunju Lee et al.
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Three Surface Exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, Promote Resistance to Opsonophagocytic Killing by Human Neutrophils
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The Proline-Rich Region of Pneumococcal Surface Proteins A and C Contains Surface-Accessible Epitopes Common to All Pneumococci and Elicits Antibody-Mediated Protection against Sepsis
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Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine
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Effect of Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis
Heather E. Hsu et al.
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Vaccine-induced human antibodies to PspA augment complement C3 deposition on Streptococcus pneumoniae
Martina M. Ochs et al.
MICROBIAL PATHOGENESIS (2008)
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
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PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation
Jie Li et al.
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Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition
M. Darrieux et al.
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Herd immunity and pneumococcal conjugate vaccine: A quantitative model
Michael Haber et al.
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George R. Siber et al.
VACCINE (2007)
Invasive pneumococcal disease caused by nonvaccine serotypes among Alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage
Rosalyn J. Singleton et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
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Pneumolysin, PspA, and PspC contribute to pneumococcal evasion of early innate immune responses during bacteremia in mice
Lisa R. Quin et al.
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Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model
Abiodun D. Ogunniyi et al.
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Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae
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Development and validation of a fourfold multiplexed opsonization assay (MOPA4) for pneumococcal antibodies
Robert L. Burton et al.
CLINICAL AND VACCINE IMMUNOLOGY (2006)
Indirect effect of conjugate vaccine on adult carriage of Streptococcus pneumoniae:: An explanation of trends in invasive pneumococcal disease
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JOURNAL OF INFECTIOUS DISEASES (2006)
Capsule does not block antibody binding to PspA, a surface virulence protein of Streptococcus pneumoniae
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Pneumococcal surface protein A (PspA) family distribution among clinical isolates from adults over 50 years of age collected in seven countries
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Rapid multiplex assay for serotyping pneumococci with monoclonal and polyclonal antibodies
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Typing of pneumococcal surface protein A (PspA) in Streptococcus pneumoniae isolated during epidemiological surveillance in Brazil:: towards novel pneumococcal protein vaccines
MCC Brandileone et al.
VACCINE (2004)
PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin
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INFECTION AND IMMUNITY (2004)
Characterization of antibodies to PspA and PsaA in adults over 50 years of age with invasive pneumococcal disease
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The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection
B Ren et al.
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Clinical effectiveness of seven-valent pneumococcal conjugate vaccine (Prevenaro®) against invasive pneurnococcal diseases:: prospects for children in France
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Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface
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Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae
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Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H
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Avidity, potency, and cross-reactivity of monoclonal antibodies to pneumococcal capsular polysaccharide serotype 6B
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Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA
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Hic, a novel surface protein of Streptococcus pneumoniae that interferes with complement function
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Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media
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Diversity of PspA:: Mosaic genes and evidence for past recombination in Streptococcus pneumoniae
SK Hollingshead et al.
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Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules
GS Nabors et al.
VACCINE (2000)
The potential to use PspA and other pneumococcal proteins to elicit protection against pneumococcal infection
DE Briles et al.
VACCINE (2000)
Human antibodies to pneumococcal surface protein A in health and disease
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PEDIATRIC INFECTIOUS DISEASE JOURNAL (2000)