期刊
CLINICAL AND VACCINE IMMUNOLOGY
卷 19, 期 10, 页码 1697-1699出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00381-12
关键词
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资金
- NIH [RO1-A1-070236, RO1-FDAD003369]
- Cancer Immunobiology Center
- Horchow Foundation
There is no FDA-approved vaccine for the potent plant toxin ricin. We have developed a recombinant ricin vaccine, RiVax. Without adjuvant it is safe and immunogenic in mice, rabbits, and humans. Based on our studies in mice, we now report the results of a small clinical trial with Alhydrogel-adsorbed RiVax.
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