期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 54, 期 32, 页码 9203-9208出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201504337
关键词
antibiotic; natural products; structural revision; total synthesis; transannular Diels-Alder reaction
资金
- National Institutes of Health (USA) [AI055475]
- Cancer Prevention & Research Institute of Texas (CPRIT)
- Welch Foundation
- National Science Foundation Graduate Research Fellowship Program [DGE-1144086]
- Fulbright India
The total synthesis and structural revision of antibiotic CJ-16,264 is described. Starting with citronellal, the quest for the target molecule featured a novel bis-transannular Diels-Alder reaction that casted stereoselectively the decalin system and included the synthesis of six isomers before demystification of its true structure.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据