期刊
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
卷 38, 期 12, 页码 834-845出版社
WILEY
DOI: 10.1111/j.1440-1681.2011.05618.x
关键词
chemical imaging; liver; magnetic resonance imaging contrast agents; X-ray fluorescence
资金
- MIUR [RBIN04HC3S]
1. Spatially resolved X-ray fluorescence (XRF) spectroscopy with synchrotron radiation is a technique that allows imaging and quantification of chemical elements in biological specimens with high sensitivity. In the present study, we applied XRF techniques at a macro and micro level to carry out drug distribution studies on ex vivo models to confirm the hepatobiliary disposition of the Gd-based magnetic resonance imaging contrast agent B22956/1.
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