期刊
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
卷 175, 期 3, 页码 336-348出版社
WILEY
DOI: 10.1111/cei.12185
关键词
anti-NMDA receptor encephalitis; limbic encephalitis; paraneoplastic antibodies; paraneoplastic syndromes
类别
资金
- Euroimmun, Lubeck, Germany
- ICREA Funding Source: Custom
Paraneoplastic neurological syndromes are immune-mediated erroneous attacks on the central or peripheral nervous systems, or both, directed originally against the tumour itself. They have been known for more than 40 years, but recently the discovery of new subgroups of paraneoplastic encephalitis syndromes with a remarkably good response to immune therapy has ignited new clinical and scientific interest. Knowledge of these subgroups and their associated autoantibodies is important in therapeutic decision-making. However, the abundance of new autoantibodies and syndromes can be confusing. This review paper summarizes current knowledge and new developments in the field of paraneoplastic neurological syndromes, their classification, pathophysiology and treatment.
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