期刊
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
卷 167, 期 2, 页码 206-215出版社
OXFORD UNIV PRESS
DOI: 10.1111/j.1365-2249.2011.04516.x
关键词
cancer vaccine; glycolipid; glycosylation; immunotherapy; monoclonal antibody
类别
资金
- MRC
- Lewis Trust
Research into aberrant glycosylation and over-expression of glycolipids on the surface of the majority of cancers, coupled with a knowledge of glycolipids as functional molecules involved in a number of cellular physiological pathways, has provided a novel area of targets for cancer immunotherapy. This has resulted in the development of a number of vaccines and monoclonal antibodies that are showing promising results in recent clinical trials.
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