期刊
CLINICA CHIMICA ACTA
卷 414, 期 -, 页码 65-69出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.cca.2012.08.016
关键词
Metabolomics; Urine; Metabolites; Biomarkers; Diagnosis; System biology
资金
- Key Program of the Natural Science Foundation of the State [90709019]
- National Key Program on the Subject of Drug Innovation [2009ZX09502-005]
- National Specific Program on the Subject of Public Welfare [200807014]
- National Program for Key Basic Research Projects in China [2005CB523406]
Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this approach is its ability to assess global metabolic profiles to enhance pathologic characterization. Urine is an ideal bio-medium for disease study because it is readily available, easily obtained and less complex than other body fluids. Ease of collection allows for serial sampling to monitor disease and therapeutic response. Because of this potential, this paper will review urine metabolomic analysis, discuss its significance in the post-genomic era and highlight the specific roles of endogenous small molecule metabolites in this emerging field. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据