期刊
CLEFT PALATE-CRANIOFACIAL JOURNAL
卷 47, 期 5, 页码 454-468出版社
SAGE PUBLICATIONS INC
DOI: 10.1597/09-172
关键词
alveolar clefts; bone bridge formation; cleft lip and palate; monocortical mandibular bone graft; secondary bone grafting; tooth eruption
资金
- Japan Society for the Promotion of Science [19592278]
- Grants-in-Aid for Scientific Research [19592278] Funding Source: KAKEN
Objective: To assess and develop a monocortical mandibular bone grafting procedure for reconstruction of alveolar cleft. Design: Prospective study. Setting: Hokkaido University Hospital. Patients: Forty-two consecutive Japanese patients who had been treated for a total of 48 clefts according to a strict clinical protocol. Mean age at bone grafting was 6 years 11 months. Interventions: Bone grafting was performed by harvesting lateral cortical bone plates from the symphysis and/or body and then placing them on the labial and palatal openings of the alveolar process defect. No particulate bone grafts were packed into the bony cavity. Mean follow-up after bone grafting was 37 months. Main Outcome Measures: Status of the grafted area and eruption of cleft-adjacent teeth were assessed prospectively using computed tomography and periapical radiography. Results: At 6 months postoperatively, computed tomography showed sufficient bone bridge formation at the cleft site in 85.4% of clefts. Periapical radiography showed >= 75% of the root surfaces of cleft-adjacent teeth were covered with spanning bone in 83.3% of clefts. In 92.6% of clefts in which the cleft-adjacent canine was uncovered with bone during follow-up, the canines erupted spontaneously. Conclusions: Monocortical mandibular bone grafting appears extremely effective for sufficient bone bridge formation and facilitation of cleft-adjacent teeth eruption. The procedure is advantageous in that the quantity of bone required per unit volume of cleft defect is relatively reduced, and larger clefts can thus be treated.
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