期刊
CIRP ANNALS-MANUFACTURING TECHNOLOGY
卷 60, 期 1, 页码 271-274出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.cirp.2011.03.116
关键词
Biomedical; Extrusion; Rapid prototyping
The production methodology of 3D constructs for tissue regeneration is usually a complex discontinuous process involving three different stages: (1) production of 3D matrices; (2) matrix sterilisation and cell seeding; (3) in vitro dynamic cell culture. This paper presents a novel automated bench-top manufacturing system called BioCell Printing, designed for the integrated, continuous and fully automated production and in vitro dynamic culture of tissue engineering constructs. The BioCell aims at the rapid production of tissue-engineered substitutes with low risk of contamination, increasing the chances of direct clinical application. (C) 2011 CIRP.
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