期刊
CIRCULATION RESEARCH
卷 112, 期 11, 页码 1506-1519出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/CIRCRESAHA.113.300512
关键词
immune responses; inflammation; platelets; vasculopathy; vessel diseases
资金
- National Institutes of Health
- National Center for Research Resources [R37HL044525, R01HL092746, R01HL066277, R01HL100121, R01HL091754, K23HL092161, HL12311, ULI-RR025764]
Platelets are chief effector cells in hemostasis. In addition, they are multifaceted inflammatory cells with functions that span the continuum from innate immune responses to adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of vascular disorders and vasculopathies. Recently identified inflammatory and immune activities provide insights into the biology of these versatile blood cells that are directly relevant to human vascular diseases.
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