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Kyle Niessen et al.
JOURNAL OF CELL BIOLOGY (2008)
Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development
Frances A. High et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Notch signaling in blood vessels - Who is talking to whom about what?
Jennifer J. Hofmann et al.
CIRCULATION RESEARCH (2007)
Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function
Mei Xin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The Notch regulator MAML1 interacts with p53 and functions as a coactivator
Yongtong Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Tetralogy of Fallot and alterations in vascular endothelial growth factor-A signaling and Notch signaling in mouse embryos solely expressing the VEGF120 isoform
Nynke M. S. van den Akker et al.
CIRCULATION RESEARCH (2007)
Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition
Andreas Fischer et al.
CIRCULATION RESEARCH (2007)
Notch signaling is essential for ventricular chamber development
Joaquin Grego-Bessa et al.
DEVELOPMENTAL CELL (2007)
Delta-like ligand 4 (DII4) is induced by VEGF as a negative regulator of angiogenic sprouting
I. B. Lobov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2
Hiroki Kokubo et al.
DEVELOPMENT (2007)
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation
Frances A. High et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
The Delta intracellular domain mediates TGF-β/Activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway
Masahiro Hiratochi et al.
NUCLEIC ACIDS RESEARCH (2007)
Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop
Gonzalo Del Monte et al.
DEVELOPMENTAL DYNAMICS (2007)
CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression
Jarrett T. Whelan et al.
CELL CYCLE (2007)
Control of cardiogenesis by the Notch pathway
Thierry Pedrazzini
TRENDS IN CARDIOVASCULAR MEDICINE (2007)
Cell and molecular biology of Notch
Ulla-Maj Fiuza et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors
Joshua B. Rutenberg et al.
DEVELOPMENT (2006)
Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis
Marcus Glittenberg et al.
EMBO JOURNAL (2006)
Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jκ-dependent pathway
Hiroshi Doi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
RBP-Jκ-dependent notch signaling is dispensable for mouse early embryonic development
Celine Souilhol et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway
Ryan McDaniell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Smooth muscle α-actin is a direct target of Notch/CSL
Michela Noseda et al.
CIRCULATION RESEARCH (2006)
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice
Apostolos Klinakis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Jagged1 (JAG1) mutations in alagille syndrome:: Increasing the mutation detection rate
DM Warthen et al.
HUMAN MUTATION (2006)
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse
Y Watanabe et al.
DEVELOPMENT (2006)
Dll4-selective Notch signaling induces ephrinB2 gene expression in endothelial cells
T Iso et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis
HX Shen et al.
GENES & DEVELOPMENT (2006)
Recent insights into the role of Notch signaling in tumorigenesis
KG Leong et al.
BLOOD (2006)
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
LJ Ma et al.
DEVELOPMENT (2005)
HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box
H Doi et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Notch signaling is an important regulator of type 2 immunity
LL Tu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart
JK Wang et al.
DEVELOPMENTAL BIOLOGY (2005)
Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts
A Fischer et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Mutations in NOTCH1 cause aortic valve disease
V Garg et al.
NATURE (2005)
Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles
R Benedito et al.
GENE EXPRESSION PATTERNS (2005)
Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2
MK Singh et al.
DEVELOPMENT (2005)
VE-cadherin is not required for the fort-nation of nascent blood vessels but acts to prevent their disassembly
CV Crosby et al.
BLOOD (2005)
Notch signaling represses myocardin-induced smooth muscle cell differentiation
A Proweller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The role of notch in modeling and maintaining the vasculature
A Karsan
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2005)
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis
HY Chen et al.
DEVELOPMENT (2004)
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation
M Noseda et al.
CIRCULATION RESEARCH (2004)
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
A Fischer et al.
GENES & DEVELOPMENT (2004)
Vascular anomalies in Alagille syndrome - A significant cause of morbidity and mortality
BM Kamath et al.
CIRCULATION (2004)
Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development
Z Harrelson et al.
DEVELOPMENT (2004)
Lineage and morphogenetic analysis of the cardiac valves
FJ de Lange et al.
CIRCULATION RESEARCH (2004)
Mastermind critically regulates Notch-mediated lymphoid cell fate decisions
I Maillard et al.
BLOOD (2004)
Heart valve development - Endothelial cell signaling and differentiation
EJ Armstrong et al.
CIRCULATION RESEARCH (2004)
Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction
H Kokubo et al.
CIRCULATION RESEARCH (2004)
Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells
V Kaartinen et al.
DEVELOPMENT (2004)
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
LA Timmerman et al.
GENES & DEVELOPMENT (2004)
Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice
M Asahi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cardiac chamber formation: Development, genes, and evolution
AFM Moorman et al.
PHYSIOLOGICAL REVIEWS (2003)
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
K Jiao et al.
GENES & DEVELOPMENT (2003)
Glycosylation regulates notch signalling
N Haines et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division
Z Han et al.
DEVELOPMENT (2003)
Heart development: molecular insights into cardiac specification and early morphogenesis
T Brand
DEVELOPMENTAL BIOLOGY (2003)
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression
LT Krebs et al.
GENES & DEVELOPMENT (2003)
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing card cardiomyogenesis
T Schroeder et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Node and midline defects are associated with left-right development in Delta1 mutant embryos
GKH Przemeck et al.
DEVELOPMENT (2003)
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis
ZJ Liu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2
Y Sakata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome
DB McElhinney et al.
CIRCULATION (2002)
Presenilins mediate a dual intramembranous γ-secretase cleavage of Notch-1
M Okochi et al.
EMBO JOURNAL (2002)
Characterization of Notch receptor expression in the developing mammalian heart and liver
KM Loomes et al.
AMERICAN JOURNAL OF MEDICAL GENETICS (2002)
CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?
AM Arias et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2002)
Tetralogy of Fallot and other congenital heart defects in Hey2 mutant mice
J Donovan et al.
CURRENT BIOLOGY (2002)
Mouse gridlock:: No aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice
M Gessler et al.
CURRENT BIOLOGY (2002)
Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation
WH Ge et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
aph-1 and pen-2 are required for notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation
R Francis et al.
DEVELOPMENTAL CELL (2002)
The incidence of congenital heart disease
JIE Hoffman et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)
HERP1 is a cell type-specific primary target of Notch
T Iso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor
Y Hu et al.
DEVELOPMENTAL CELL (2002)
Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning
RL Davis et al.
ONCOGENE (2001)
Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels
N Villa et al.
MECHANISMS OF DEVELOPMENT (2001)
Induction of cyclin D1 transcription and CDK2 activity by Notchic:: Implication for cell cycle disruption in transformation by Notchic
C Ronchini et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm
RG Kelly et al.
DEVELOPMENTAL CELL (2001)
Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart
RY Kim et al.
DEVELOPMENTAL BIOLOGY (2001)
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
A Rangarajan et al.
EMBO JOURNAL (2001)
Ligand-induced signaling in the absence of furin processing of Notch1
G Bush et al.
DEVELOPMENTAL BIOLOGY (2001)
Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development:: Evidence for BMP2 induction of Tbx2
M Yamada et al.
DEVELOPMENTAL BIOLOGY (2000)
Degradation of type IV collagen by matrix metalloproteinases is an important step in the epithelial-mesenchymal transformation of the endocardial cushions
WM Song et al.
DEVELOPMENTAL BIOLOGY (2000)
Mesp1 expression is the earliest sign of cardiovascular development
Y Saga et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2000)
The Notch signalling regulator Fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DxD
S Munro et al.
CURRENT BIOLOGY (2000)
Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules
DJ Moloney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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