4.7 Review

Notch and Vascular Smooth Muscle Cell Phenotype

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Notch signaling regulates platelet-derived growth factor receptor-β expression in vascular smooth muscle cells

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Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-β in vascular morphogenesis

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Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

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Transforming growth factor-β(TGF-β1) down-regulates Notch3 in fibroblasts to promote smooth muscle gene expression

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Notch signaling in vascular smooth muscle cells is required to pattern the cerebral vasculature

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Mammalian NOTCH-1 activates β1 integrins via the small GTPase R-Ras

Philip S. Hodkinson et al.

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Notch signaling in vascular development and physiology

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Vascular development in early ovine gestation: carotid smooth muscle function, phenotype, and biochemical markers

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Programming smooth muscle plasticity with chromatin dynamics

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The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo

Marie Monet et al.

HUMAN MOLECULAR GENETICS (2007)

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Notch ligand delta-like 1 is essential for postnatal arteriogenesis

Anne Limbourg et al.

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Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

Arndt F. Siekmann et al.

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An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

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Critical role of endothelial Notch1 signaling in postnatal angiogenesis

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Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jκ-dependent pathway

Hiroshi Doi et al.

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A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula

Kevin M. Vogeli et al.

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Smooth muscle α-actin is a direct target of Notch/CSL

Michela Noseda et al.

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Notch receptor encodes two structurally separable functions in Drosophila:: A genetic analysis

T Langdon et al.

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Phenotypic modulation of intima and media smooth muscle cells in fatal cases of coronary artery lesion

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Notch1 augments NF-κB activity by facilitating its nuclear retention

HM Shin et al.

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Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo

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Notch-mediated CBF-1/RBP-Jκ-dependent regulation of human vascular smooth muscle cell phenotype in vitro

D Morrow et al.

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Hypoxia requires Notch signaling to maintain the undifferentiated cell state

MV Gustafsson et al.

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Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling

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Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

TR Carlson et al.

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The role of circulating precursors in vascular repair and lesion formation

M Sata et al.

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Functional redundancy of the Notch gene family during mouse embryogenesis:: Analysis of Notch gene expression in Notch3-deficient mice

T Kitamoto et al.

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Essential role of endothelial Notch1 in angiogenesis

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The roles of receptor and ligand endocytosis in regulating Notch signaling

R Le Borgne et al.

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Cyclic strain inhibits notch receptor signaling in vascular smooth muscle cells in vitro

D Morrow et al.

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Notch signaling represses myocardin-induced smooth muscle cell differentiation

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Molecular determinants of vascular smooth muscle cell diversity

T Yoshida et al.

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GATA-6 regulates genes promoting synthetic functions in vascular smooth muscle cells

JJ Lepore et al.

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Vascular anomalies in Alagille syndrome - A significant cause of morbidity and mortality

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Atherosclerotic plaque smooth muscle cells have a distinct phenotype

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Mastermind recruits CycC:CDK8 to phosphorylate the notch ICD and coordinate activation with turnover

CJ Fryer et al.

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Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

NW Gale et al.

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Id family of transcription factors and vascular lesion formation

S Forrest et al.

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Dosage-sensitive requirement for mouse D114 in artery development

A Duarte et al.

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Notch activation induces endothelial cell cycle arrest and participates in contact inhibition:: Role of p21Cip1 repression

M Noseda et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

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Arterial smooth muscle cell heterogeneity - Implications for atherosclerosis and restenosis development

HY Hao et al.

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Positive and negative regulation of the γ-secretase activity by nicastrin in a murine model

JH Li et al.

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HRT1 modulates vascular smooth muscle cell proliferation and apoptosis

WL Wang et al.

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Phosphorylation by glycogen synthase kinase-3β down-regulates Notch activity, a link for Notch and Wnt pathways

L Espinosa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

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Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells

DG Sedding et al.

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Article Cardiac & Cardiovascular Systems

Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes

T Yoshida et al.

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Notch signaling in vascular development

T Iso et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)

Review Cell Biology

HES and HERP families: Multiple effectors of the Notch signaling pathway

T Iso et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2003)

Review Anatomy & Morphology

Molecular control of arterial-venous blood vessel identity

RH Adams

JOURNAL OF ANATOMY (2003)

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Endocytic trafficking during Drosophila development

M Gonzalez-Gaitan

MECHANISMS OF DEVELOPMENT (2003)

Article Multidisciplinary Sciences

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling

H Karlström et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Hematology

Expression profiling identifies 147 genes contributing to a unique primate neointimal smooth muscle cell phenotype

RL Geary et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)

Review Cell Biology

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

AM Arias et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2002)

Article Biochemistry & Molecular Biology

Activated Notch4 inhibits angiogenesis:: Role of β1-integrin activation

KG Leong et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate

P Ramain et al.

CURRENT BIOLOGY (2001)

Article Multidisciplinary Sciences

Gridlock signalling pathway fashions the first embryonic artery

TP Zhong et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

p300 acts as a transcriptional coactivator for mammalian Notch-1

F Oswald et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Article Biochemistry & Molecular Biology

The smooth muscle myosin heavy chain gene exhibits smooth muscle subtype-selective modular regulation in vivo

I Manabe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Developmental Biology

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels

N Villa et al.

MECHANISMS OF DEVELOPMENT (2001)

Article Biochemistry & Molecular Biology

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian sel-10 homolog

C Öberg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

HERP, a new primary target of notch regulated by ligand binding

T Iso et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Article Multidisciplinary Sciences

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

H Uyttendaele et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Notch signaling targets the Wingless responsiveness of a Ubx visceral mesoderm enhancer in Drosophila

N Lawrence et al.

CURRENT BIOLOGY (2001)

Article Developmental Biology

Ligand-induced signaling in the absence of furin processing of Notch1

G Bush et al.

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Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury

CP Regan et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)

Article Developmental Biology

Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos

C Leimeister et al.

MECHANISMS OF DEVELOPMENT (2000)

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Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1

SS Huppert et al.

NATURE (2000)

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The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

A Joutel et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)