4.1 Review

Regulation of splicing by SR proteins and SR protein-specific kinases

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RS domains contact the pre-mRNA throughout spliceosome assembly

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Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins

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Involvement of SR proteins in mRNA surveillance

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A molecular link between SR protein dephosphorylation and mRNA export

YQ Huang et al.

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Processive phosphorylation of alternative splicing factor/splicing factor 2

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SR splicing factors serve as adapter proteins for TAP-dependent mRNA export

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Signal-dependent regulation of splicing via phosphorylation of Sam68

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The SR protein SRp38 represses splicing in M phase cells

CS Shin et al.

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Nuclear export and retention signals in the RS domain of SR proteins

D Cazalla et al.

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Transportin-SR2 mediates nuclear import of phosphorylated SR proteins

MC Lai et al.

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SC35 plays a role in T cell development and alternative splicing of CD45

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The structure of Sky1p reveals a novel mechanism for constitutive activity

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Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation

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A human importin-β family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins

MC Lai et al.

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Exonic splicing enhancer motif recognized by human SC35 under splicing conditions

HX Liu et al.

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