4.1 Review

Epigenetic regulation of genomic integrity

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ATM stabilizes DNA double-strand-break complexes during V(D)J recombination

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H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

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Histone H4-K16 acetylation controls chromatin structure and protein interactions

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The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1

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Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

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Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

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NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage

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p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage

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The p48 subunit of the damaged-DNA binding protein DDB associates with the CBP/p300 family of histone acetyltransferase

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