期刊
CHINESE SCIENCE BULLETIN
卷 58, 期 17, 页码 2027-2031出版社
SCIENCE PRESS
DOI: 10.1007/s11434-013-5708-3
关键词
digital color analysis; gold nanoparticles; colorimetric; quinidine
资金
- National Natural Science Foundation of China [21035005]
- National Special Major Project of Science and Technology for Creation of New Drugs [20102X09401-306-1-4]
In this contribution, we developed a novel digital color analysis of gold nanoparticles (AuNPs) for pharmaceutical detection by choosing quinidine as an example. It was found that the color of AuNPs colloid solution changed from red to blue in the presence of different concentrations of quinidine, and the color information of each solution could be digitalized with tricolor (RGB) system. Under the optimum conditions, the R value of the solution was found to be linear with the natural logarithm of concentration of quinidine in the range of 112-384 nmol/L. This method has the advantages of rapid, economical and simple, and can serve as a potential alternative to traditional spectrophotometry for practical use.
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