A General and Highly Selective Method for the Asymmetric Synthesis of Trifluoromethyl-Substituted α- and β-Aminophosphonates

A highly selective method for the asymmetric formation of trifluoromethyl-substituted - and -aminophosphonates was described. The reaction proceeded with high yields and good to excellent diastereoselectivity. The product can be easily converted into corresponding trifluoromethyl-substituted aminophosphoric acids.