期刊
CHINESE JOURNAL OF CHEMISTRY
卷 30, 期 5, 页码 1075-1082出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201100560
关键词
palladium; copper-catalyst; microwave; isoquinolines; tandem reaction; coupling cyclization
资金
- National Natural Science Foundation of China [21002038]
- CCNU from the Colleges' Basic Research and Operation of MOE [CCNU09A01014]
A novel three-component reaction of o-bromobenzaldehyde, terminal alkynes and tert-butyl amine has been established, which proceeded smoothly to give 3-substituted isoquinolines in good yields in the presence of palladium/copper catalysts under microwave irradiation.
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