期刊
CHINESE CHEMICAL LETTERS
卷 24, 期 11, 页码 993-996出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2013.06.005
关键词
SILLP; Imidazole; Phenanthroimidazole; Ionic liquid; Three-component reaction; Anti-microbial activities
资金
- Research Council of University of Guilan
An efficient method for the synthesis of imidazole derivatives by a three-component condensation of benzil or 9,10-phenanthrenequinone, aldehydes and ammonium acetate using supported ionic liquid-like phase (SILLP) catalyst under ultrasonic irradiation or classical heating conditions is reported. The present methodology offers several advantages, such as excellent yields, simple procedures, short reaction times, simple work-up and mild conditions. The catalyst is easily separated from the products by filtration and also exhibits remarkable reusable activity. These highly substituted imidazoles were also evaluated for their anti-microbial activity. (C) 2013 Manouchehr Mamaghani. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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