4.7 Article

One-pot three-component synthesis of α-amino nitriles catalyzed by nano powder TiO2 P 25

期刊

CHINESE CHEMICAL LETTERS
卷 22, 期 5, 页码 555-558

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2010.12.003

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Nano powder TiO2 P 25; alpha-Amino nitriles; One-pot three-component synthesis; Strecker reaction; Trimethylsilyl cyanide

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A simple and efficient method has been developed for the synthesis of alpha-amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me3SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature. (C) 2010 Seyed Meysam Baghbanian. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

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