期刊
CHIMIA
卷 65, 期 11, 页码 853-858出版社
SWISS CHEMICAL SOC
DOI: 10.2533/chimia.2011.853
关键词
Cell-penetrating peptides; Cellular uptake; Sensing; siRNA; Transport
资金
- NCCR
- Swiss NSF
- University of Geneva
- European Research Council (ERC)
This article summarizes the background and a few preliminary results concerning project 7 of the NCCR Chemical Biology. The general objective is to explore new concepts for cellular uptake, membrane tunneling, sensing and labeling. Emphasis is on the use of dynamic covalent chemistry for counterion activation, slow release of polyions and fluorescent probes, and the generation of activator libraries and polyions that grow and shrink.
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