期刊
CHEMOSPHERE
卷 92, 期 1, 页码 100-105出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.chemosphere.2013.02.047
关键词
Magnetic ionic liquids; Toxicity; Cell lines; Risk assessment
资金
- Fundacao para a Ciencia e Tecnologia (POCI)
- FEDER [SFRH/BD/67025/2009, SFRH/BPD/75045/2010, ERA-CHEM/0001/2008, PEst-OE/SAU/UI4013/2011, REDE/1518/REM/2005]
- Fundação para a Ciência e a Tecnologia [ERA-CHEM/0001/2008, SFRH/BD/67025/2009, SFRH/BPD/75045/2010] Funding Source: FCT
Magnetic ionic liquids (MILs) are new solvents with an interesting broad of applications however their toxicity is still an open issue. In this paper we report the toxicity of [C8MIM] and [Choline-C-n] based magnetic ionic liquids assessed in two human cell lines: normal skin fibroblasts (CRL-1502) and colorectal adenocarcinoma cells (CaCo-2), acquiring this last characteristics of human enterocytes after differentiation. The results showed that [CoCl4] and [MnCl4] are more prone to generate cytotoxicity. (C) 2013 Elsevier Ltd. All rights reserved.
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