期刊
CHEMMEDCHEM
卷 10, 期 2, 页码 233-237出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cmdc.201402416
关键词
anti-leishmanial agents; antiparasitic agents; Leishmania; peptoids
资金
- Engineering and Physical Sciences Research Council, UK
- Swiss National Science Foundation
- Engineering and Physical Sciences Research Council [1342926] Funding Source: researchfish
Peptoids, a class of peptide mimetics, have emerged as promising anti- infective agents against a range of bacterial infections. Herein we present the first study of the antiparasitic and specifically the anti- leishmanial properties of linear peptoids. Peptoids were identified as having promising activity against Leishmania mexicana axenic amastigotes, a causative agent of cutaneous leishmaniasis.
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