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Tsui-Fen Chou et al.
AUTOPHAGY (2011)
Positive Cooperativity of the p97 AAA ATPase Is Critical for Essential Functions
Shingo Nishikori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Quantitative Cell-based Protein Degradation Assays to Identify and Classify Drugs That Target the Ubiquitin-Proteasome System
Tsui-Fen Chou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations
Danilo Ritz et al.
NATURE CELL BIOLOGY (2011)
Critical Role of VCP/p97 in the Pathogenesis and Progression of Non-Small Cell Lung Carcinoma
Christopher W. Valle et al.
PLOS ONE (2011)
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
Tsui-Fen Chou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
Emilie Tresse et al.
AUTOPHAGY (2010)
Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL
S. Luo et al.
CELL DEATH AND DIFFERENTIATION (2010)
Inactivation of VCP/ter94 Suppresses Retinal Pathology Caused by Misfolded Rhodopsin in Drosophila
Ana Griciuc et al.
PLOS GENETICS (2010)
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
Jeong-Sun Ju et al.
JOURNAL OF CELL BIOLOGY (2009)
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1α turnover
Gabriela Alexandru et al.
CELL (2008)
UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97
C. Schuberth et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics
Jimmy A. Blair et al.
NATURE CHEMICAL BIOLOGY (2007)
Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality
J. M. M. Mueller et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Functional interrogation of the kinome using nucleotide acyl phosphates
Matthew P. Patricelli et al.
BIOCHEMISTRY (2007)
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
Cyril Boyault et al.
GENES & DEVELOPMENT (2007)
The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy
Philipp Christoph Janiesch et al.
NATURE CELL BIOLOGY (2007)
Central pore residues mediate the p97/VCP activity required for ERAD
Byron DeLaBarre et al.
MOLECULAR CELL (2006)
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
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NATURE CHEMICAL BIOLOGY (2005)
The crystal structure of murine p97/VCP at 3.6 Å
T Huyton et al.
JOURNAL OF STRUCTURAL BIOLOGY (2003)
The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis
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CELL (2003)
Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains
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NATURE STRUCTURAL BIOLOGY (2003)
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
YH Ye et al.
JOURNAL OF CELL BIOLOGY (2003)
ATPase activity of p97-valosin-containing protein (VCP) - D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity
CC Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities
Q Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Functional profiling of the Saccharomyces cerevisiae genome
G Giaever et al.
NATURE (2002)
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening
SL McGovern et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
YH Ye et al.
NATURE (2001)
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
B Elenbaas et al.
GENES & DEVELOPMENT (2001)
A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
HH Meyer et al.
EMBO JOURNAL (2000)
Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells
NP Dantuma et al.
NATURE BIOTECHNOLOGY (2000)