相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Compensatory mutations rescue the virus replicative capacity of VIRIP-resistant HIV-1
Emmanuel Gonzalez-Ortega et al.
ANTIVIRAL RESEARCH (2011)
Recent Advances in the DABOs Family as Potent HIV-1 non-Nucleoside Reverse Transcriptase Inhibitors
Mingyan Yu et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Advances in HIV microbicide development
Joanna S. Olsen et al.
FUTURE MEDICINAL CHEMISTRY (2011)
Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study
Marco Radi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Nonnucleoside Reverse Transcriptase Inhibitor Resistance and the Role of the Second-Generation Agents
Jessica Adams et al.
ANNALS OF PHARMACOTHERAPY (2010)
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation
Alberta Samuele et al.
ANTIVIRAL RESEARCH (2010)
Development of topical microbicides to prevent the sexual transmission of HIV
Robert W. Buckheit et al.
ANTIVIRAL RESEARCH (2010)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989-2009)
Marie-Pierre de Bethune
ANTIVIRAL RESEARCH (2010)
Inhibition of Human Immunodeficiency Virus Type 1 Infection by the Candidate Microbicide Dapivirine, a Nonnucleoside Reverse Transcriptase Inhibitor
P. Fletcher et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex
Alberta Samuele et al.
ANTIVIRAL RESEARCH (2009)
Discovery of Chiral Cyclopropyl Dihydro-Alkylthio-Benzyl-Oxopyrimidine (S-DABO) Derivatives as Potent HIV-1 Reverse Transcriptase Inhibitors with High Activity Against Clinically Relevant Mutants
Marco Radi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Recent highlights in the synthesis of highly functionalized pyrimidines
Marco Radi et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors:: S-DABOCs and DAVPs
Marco Radi et al.
CHEMMEDCHEM (2008)
5-alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile
Maxim B. Nawrozkij et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase:: Synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants
Claudia Mugnaini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Carrageenan/MIV-150 (PC-815), a combination microbicide
Jose A. Fernandez-Romero et al.
SEXUALLY TRANSMITTED DISEASES (2007)
Novel tight binding PETT, HEPT and DABO-based non-nucleoside inhibitors of HIV-1 reverse transcriptase
Osmond J. D'Cruz et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2006)
Novel broad-spectrum thiourea non-nucleoside inhibitors for the prevention of mucosal HIV transmission
Osmond J. D'Cruz et al.
CURRENT HIV RESEARCH (2006)
In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1
MM Hossain et al.
JOURNAL OF VIROLOGY (2006)
Dawn of non-nucleoside inhibitor-based anti-HIV microbicides
OJ D'Cruz et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2006)
Towards new methodologies for the synthesis of biologically interesting 6-substituted pyrimidines and 4(3H)-pyrimidinones
Elena Petricci et al.
ARKIVOC (2006)
Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity
F Manetti et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
A general, Bronsted acid-catalyzed hetero-Michael addition of nitrogen, oxygen, and sulfur nucleophiles
TC Wabnitz et al.
ORGANIC LETTERS (2003)
Selected non-nucleoside reverse transcriptase inhibitors (NNRTIs): the DABOs family
M Artico
DRUGS OF THE FUTURE (2002)
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
A Mai et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
High throughput prediction of oral absorption: Improvement of the composition of the lipid solution used in parallel artificial membrane permeation assay
K Sugano et al.
JOURNAL OF BIOMOLECULAR SCREENING (2001)
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes
F Wohnsland et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
分享论文
