相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Alkyne derivatives of isocoumarins as clickable activity-based probes for serine proteases
Ute Haedke et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study
Wouter A. van der Linden et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Cleavable linkers in chemical biology
Geoffray Leriche et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain
Jiyoun Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Bioconjugation with Strained Alkenes and Alkynes
Marjoke F. Debets et al.
ACCOUNTS OF CHEMICAL RESEARCH (2011)
Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
Lianne I. Willems et al.
ACCOUNTS OF CHEMICAL RESEARCH (2011)
An activity-based probe for high-throughput measurements of triacylglycerol lipases
John Tam et al.
ANALYTICAL BIOCHEMISTRY (2011)
Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation
Mark R. Karver et al.
BIOCONJUGATE CHEMISTRY (2011)
Monoacylglycerol Lipase Exerts Dual Control over Endocannabinoid and Fatty Acid Pathways to Support Prostate Cancer
Daniel K. Nomura et al.
CHEMISTRY & BIOLOGY (2011)
Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes
Laura E. Edgington et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Discovery and Optimization of Sulfonyl Acrylonitriles as Selective, Covalent Inhibitors of Protein Phosphatase Methylesterase-1
Daniel A. Bachovchin et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
A Substrate-Free Activity-Based Protein Profiling Screen for the Discovery of Selective PREPL Inhibitors
Anna Mari Lone et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Potent and Selective Inhibitors of Glutathione S-Transferase Omega 1 That Impair Cancer Drug Resistance
Katsunori Tsuboi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
A Peptide Aldehyde Microarray for High-Throughput Profiling of Cellular Events
Hao Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)
Mingyu Hu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors
Alexander Adibekian et al.
NATURE CHEMICAL BIOLOGY (2011)
Irreversible inhibitors and activity-based probes as research tools in chemical glycobiology
Martin D. Witte et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2011)
Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a 64Cu-Labeled Activity-Based Probe
Gang Ren et al.
PLOS ONE (2011)
Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors
Daniel A. Bachovchin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Chemical Probes of Surface Layer Biogenesis in Clostridium difficile
T. H. Tam Dang et al.
ACS CHEMICAL BIOLOGY (2010)
A Cleavable Linker Based on the Levulinoyl Ester for Activity-Based Protein Profiling
Paul P. Geurink et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Bisaryl Hydrazones as Exchangeable Biocompatible Linkers
Anouk Dirksen et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)
Daniel A. Bachovchin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Two-Step Labeling of Endogenous Enzymatic Activities by Diels-Alder Ligation
Lianne I. Willems et al.
CHEMBIOCHEM (2010)
A fluopol-ABPP HTS assay to identify PAD inhibitors
Bryan Knuckley et al.
CHEMICAL COMMUNICATIONS (2010)
The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds
Ronald Orth et al.
CHEMICAL COMMUNICATIONS (2010)
Cu-free click cycloaddition reactions in chemical biology
John C. Jewett et al.
CHEMICAL SOCIETY REVIEWS (2010)
Comparative Analysis of Cleavable Azobenzene-Based Affinity Tags for Bioorthogonal Chemical Proteomics
Yu-Ying Yang et al.
CHEMISTRY & BIOLOGY (2010)
Cleavable Biotin Probes for Labeling of Biomolecules via Azide-Alkyne Cycloaddition
Janek Szychowski et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Emerging principles in protease-based drug discovery
Marcin Drag et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Fluorescence quenched quinone methide based activity probes - a cautionary tale
Jonathan D. Sellars et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
Daniel A. Bachovchin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
An Orthogonal Active Site Identification System (OASIS) for Proteomic Profiling of Natural Product
Jordan L. Meier et al.
ACS CHEMICAL BIOLOGY (2009)
Receptor-Mediated Targeting of Cathepsins in Professional Antigen Presenting Cells
Ulrik Hillaert et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Evaluation of α,β-unsaturated ketone-based probes for papain-family cysteine proteases
Zhimou Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild-Type and Bortezomib-Adapted Leukaemic Cell Lines
Jerome Clerc et al.
CHEMBIOCHEM (2009)
Activity-Based Probes for Monitoring Postproline Protease Activity
Eduard Sabido et al.
CHEMBIOCHEM (2009)
Activity-Based Protein Profiling Reveals Broad Reactivity of the Nerve Agent Sarin
Adriaan W. Tuin et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2009)
Useful Tools for Biomolecule Isolation, Detection, and Identification: Acylhydrazone-Based Cleavable Linkers
Ki Duk Park et al.
CHEMISTRY & BIOLOGY (2009)
β-Lactam Probes As Selective Chemical-Proteomic Tools for the Identification and Functional Characterization of Resistance Associated Enzymes in MRSA
Isabell Staub et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Diversity of Serine Hydrolase Activities of Unchallenged and Botrytis-infected Arabidopsis thaliana
Farnusch Kaschani et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes
Daniel A. Bachovchin et al.
NATURE BIOTECHNOLOGY (2009)
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes
Laura E. Edgington et al.
NATURE MEDICINE (2009)
Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using 'click chemistry'
Farnusch Kaschani et al.
PLANT JOURNAL (2009)
Comparative Assessment of Substrates and Activity Based Probes as Tools for Non-Invasive Optical Imaging of Cysteine Protease Activity
Galia Blum et al.
PLOS ONE (2009)
beta-lactones as privileged structures for the active-site labeling of versatile bacterial
Thomas Boettcher et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
β-lactams as selective chemical probes for the in vivo labeling of bacterial enzymes involved in cell wall biosynthesis, antibiotic resistance, and virulence
Isabell Staub et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum
Shirin Arastu-Kapur et al.
NATURE CHEMICAL BIOLOGY (2008)
Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes
Martijn Verdoes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
Galia Blum et al.
NATURE CHEMICAL BIOLOGY (2007)
Proteomics evaluation of chemically cleavable activity-based probes
Marko Fonovic et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Assessing enzyme activities using stable isotope Labeling and mass spectrometry
Patrick A. Everley et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Activity-based protein profiling for type I methionine aminopeptidase by using photo-affinity trimodular probes
Wen-Wei Qiu et al.
CHEMBIOCHEM (2007)
Tagging and detection strategies for activity-based proteomics
Amir M. Sadaghiani et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2007)
Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP) - a general method for mapping sites of probe modification in proteomes
Eranthie Weerapana et al.
NATURE PROTOCOLS (2007)
Catch-and-release reagents for broadscale quantitative proteomics analyses
Carlos A. Gartner et al.
JOURNAL OF PROTEOME RESEARCH (2007)
Activity-based fingerprinting and inhibitor discovery of cysteine proteases in a microarray
Mahesh Uttamchandani et al.
CHEMICAL COMMUNICATIONS (2007)
A mild chemically cleavable linker system for functional proteomic applications
Steven H. L. Verhelst et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes
Alicia B. Berger et al.
MOLECULAR CELL (2006)
High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: Mutant viruses altered in its active-site cysteine or histidine are viable
Jianlei Wang et al.
JOURNAL OF VIROLOGY (2006)
Development of activity-based probes for trypsin-family serine proteases
ZY Pan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I cathepsin C
F Yuan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Proteomic profiling of metalloprotease activities with cocktails of active-site probes
SA Sieber et al.
NATURE CHEMICAL BIOLOGY (2006)
Tumour microenvironment - Opinion - Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
CM Overall et al.
NATURE REVIEWS CANCER (2006)
Mechanism-based probe for the analysis of cathepsin cysteine proteases in living cells
Howard C. Hang et al.
ACS CHEMICAL BIOLOGY (2006)
Targeting proteases: successes, failures and future prospects
Boris Turk
NATURE REVIEWS DRUG DISCOVERY (2006)
Activity-based fingerprinting of proteases
R Srinivasan et al.
CHEMBIOCHEM (2006)
A general solid phase method for the preparation of diverse azapeptide probes directed against cysteine proteases
D Kato et al.
ORGANIC LETTERS (2005)
A streamlined platform for high-content functional proteomics of primary human specimens
N Jessani et al.
NATURE METHODS (2005)
Dynamic imaging of protease activity with fluorescently quenched activity-based probes
G Blum et al.
NATURE CHEMICAL BIOLOGY (2005)
A tandem orthogonal proteolysis strategy for high-content chemical proteomics
AE Speers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Activity-based probes that target diverse cysteine protease families
D Kato et al.
NATURE CHEMICAL BIOLOGY (2005)
Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases
SHL Verhelst et al.
CHEMBIOCHEM (2005)
Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells
S Mahrus et al.
CHEMISTRY & BIOLOGY (2005)
Enzyme family-specific and activity-based screening of chemical libraries using enzyme microarrays
DP Funeriu et al.
NATURE BIOTECHNOLOGY (2005)
Site-specific labeling of proteins with small molecules in live cells
I Chen et al.
CURRENT OPINION IN BIOTECHNOLOGY (2005)
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
JA Joyce et al.
CANCER CELL (2004)
Profiling enzyme activities in vivo using click chemistry methods
AE Speers et al.
CHEMISTRY & BIOLOGY (2004)
Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells
H Ovaa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Microarray platform for profiling enzyme activities in complex proteomes
SA Sieber et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Developing novel activity-based fluorescent probes that target different classes of proteases
Q Zhu et al.
CHEMICAL COMMUNICATIONS (2004)
Developing photoactive affinity probes for proteomic profiling: Hydroxamate-based probes for metalloproteases
EWS Chan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases
PF van Swieten et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Enzyme microarrays: On-chip determination of inhibition constants based on affinity-label defection of enzymatic activity
J Eppinger et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
PNA-encoded protease substrate microarrays
N Winssinger et al.
CHEMISTRY & BIOLOGY (2004)
Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: A caution in data interpretation
P Pozarowski et al.
CYTOMETRY PART A (2003)
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors:: when reaction mechanism is more important than specificity
J Rozman-Pungercar et al.
CELL DEATH AND DIFFERENTIATION (2003)
Activity-based protein profiling in vivo using a copper(I)-catalyzed azide-alkyne [3+2] cycloaddition
AE Speers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Developing a strategy for activity-based detection of enzymes in a protein microarray
GYJ Chen et al.
CHEMBIOCHEM (2003)
Solid-phase synthesis of peptide vinyl sulfones as potential inhibitors and activity-based probes of cysteine proteases
G Wang et al.
ORGANIC LETTERS (2003)
Chemistry in living cells: Detection of active proteasomes by a two-step labeling strategy
H Ovaa et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
A role for the protease falcipain 1 in host cell invasion by the human malaria parasite
DC Greenbaum et al.
SCIENCE (2002)
Irreversible inhibitors of serine, cysteine, and threonine proteases
JC Powers et al.
CHEMICAL REVIEWS (2002)
Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme
A Borodovsky et al.
CHEMISTRY & BIOLOGY (2002)
Profiling protein function with small molecule microarrays
N Winssinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness
N Jessani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
SE Ong et al.
MOLECULAR & CELLULAR PROTEOMICS (2002)
Cancer therapy - Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
LM Coussens et al.
SCIENCE (2002)
A Ca2+ switch aligns the active site of calpain
T Moldoveanu et al.
CELL (2002)
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14
A Borodovsky et al.
EMBO JOURNAL (2001)
Lysosomal cysteine proteases: facts and opportunities
V Turk et al.
EMBO JOURNAL (2001)
Profiling serine hydrolase activities in complex proteomes
D Kidd et al.
BIOCHEMISTRY (2001)
Large-scale analysis of the yeast proteome by multidimensional protein identification technology
MP Washburn et al.
NATURE BIOTECHNOLOGY (2001)
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA):: Correlation with DNA fragmentation
E Bedner et al.
EXPERIMENTAL CELL RESEARCH (2000)
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools
D Greenbaum et al.
CHEMISTRY & BIOLOGY (2000)
Cell surface engineering by a modified Staudinger reaction
E Saxon et al.
SCIENCE (2000)
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
M Bogyo et al.
CHEMISTRY & BIOLOGY (2000)
分享论文
