4.5 Review

Structure of the Glucocorticoid Receptor, a Flexible Protein That Can Adapt to Different Ligands

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

The X-ray Structure of RU486 Bound to the Progesterone Receptor in a Destabilized Agonistic Conformation

Hans C. A. Raaijmakers et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Biochemistry & Molecular Biology

New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects

Adali Pecci et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2009)

Review Endocrinology & Metabolism

Minireview: Latest Perspectives on Antiinflammatory Actions of Glucocorticoids

Karolien De Bosscher et al.

MOLECULAR ENDOCRINOLOGY (2009)

Article Multidisciplinary Sciences

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

Jamie T. Bridgham et al.

NATURE (2009)

Article Multidisciplinary Sciences

Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor

Keith Biggadike et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Chemistry, Medicinal

The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist

Kevin P. Madauss et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Review Biochemistry & Molecular Biology

Nuclear receptor drug discovery

Taosheng Chen

CURRENT OPINION IN CHEMICAL BIOLOGY (2008)

Article Chemistry, Medicinal

Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone

Lautaro D. Alvarez et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Review Endocrinology & Metabolism

Tissue-specific glucocorticoid action: a family affair

Katherine L. Gross et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol

Kelly Suino-Powell et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Review Cell Biology

Anti-inflammatory functions of glucocorticoid-induced genes

Andrew R. Clark

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2007)

Article Multidisciplinary Sciences

Crystal structure of an ancient protein: Evolution by conformational epistasis

Eric A. Ortlund et al.

SCIENCE (2007)

Article Pharmacology & Pharmacy

Absolute bioavailability of intranasal fluticasone furoate in healthy subjects

Ann Allen et al.

CLINICAL THERAPEUTICS (2007)

Article Endocrinology & Metabolism

A structural and in vitro characterization of asoprisnil:: A selective progesterone receptor modulator

Kevin P. Madauss et al.

MOLECULAR ENDOCRINOLOGY (2007)

Review Chemistry, Medicinal

Dissociated non-steroidal glucocorticoids: tuning out untoward effects

Michael L. Mohler et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2007)

Article Biotechnology & Applied Microbiology

Opinion - How many drug targets are there?

John P. Overington et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Chemistry, Medicinal

The nuclear receptor superfamily and drug discovery

John T. Moore et al.

CHEMMEDCHEM (2006)

Article Biochemistry & Molecular Biology

A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor

RK Bledsoe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension

J Fagart et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Resurrecting the ancestral steroid receptor: Ancient origin of estrogen signaling

JW Thornton et al.

SCIENCE (2003)

Article Pharmacology & Pharmacy

Crystallization of the human glucocorticoid receptor ligand binding domain: a step towards selective glucocorticoids

BM Necela et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2003)

Review Chemistry, Medicinal

Structure-activity relationship of nuclear receptor-ligand interactions

I Greschik et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2003)