Palladium-Catalyzed Carbonylative [3+2+1] Annulation of N-Aryl-Pyridine-2-Amines with Internal Alkynes by C-H Activation: Facile Synthesis of 2-Quinolinones

We describe here a novel procedure for the synthesis of highly substituted 2-quinolinones. By this newly developed approach, 2-quinolinone derivatives were prepared in moderate to good yields by carbonylative cyclization of N-aryl-pyridine-2-amines and internal alkynes by CH activation. Remarkably, [Mo(CO)(6)] was applied as a solid CO source and the reaction proceeded in an atom economic manner.