4.4 Article

Synthesis, Characterization, and Anticancer Activities of Pyrogallol-Based Arylspiroborates

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JOURNAL OF HETEROCYCLIC CHEMISTRY
卷 53, 期 6, 页码 1807-1812

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WILEY-BLACKWELL
DOI: 10.1002/jhet.2490

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  1. Natural Science and Engineering Research Council of Canada
  2. Mount Allison University
  3. Universite de Moncton
  4. KRESCENT program
  5. Cancer Research Society
  6. New Brunswick Innovation Foundation
  7. New Brunswick Health Research Foundation

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Arylspiroborate salts derived from pyrogallol, gallic acid, and propyl gallate have been prepared and characterized fully, including an X-ray diffraction study for the tetrabutylammonium gallic acid complex 4. The tetrabutylammonium salts were examined for their potential anticancer activities against renal cell carcinoma (RCC) cell lines, using NBu4[Bcat(2)] (cat = catecholato) as a control.

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