期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 19, 期 33, 页码 10786-10793出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201301324
关键词
discotics; molecular imaging; self-assembly; supramolecular chemical biology; supramolecular chemistry
资金
- Ministry of Education, Culture and Science [024.001.035]
- ERC [310275-BioNLight, CTMM-03O-201 Mammoth]
- STW [11022-NanoActuate]
Self-assembly of discotic molecules into supramolecular polymers offers a flexible approach for the generation of multicomponent one-dimensional columnar architectures with tuneable biomedical properties. Decoration with ligands induces specific binding of the self-assembled scaffold to biological targets. The modular design allows the easy co-assembly of different discotics for the generation of probes for targeted imaging and cellular targeting with adjustable ligand density and composition.
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