Direct sp3 C?H Amination of Nitrogen-Containing Benzoheterocycles Mediated by Visible-Light-Photoredox Catalysts

Visible-light-mediated direct sp3 C?H amination of benzocyclic amines via a-aminoalkyl radicals by using photoredox catalysts is described here. The obtained N,N-acetals were also successfully applied for carboncarbon bond forming reactions with carbon nucleophiles. The procedure is suitable for a late-stage modification of C?H bonds to C?C bonds.