相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei
Peng-Yu Yang et al.
CHEMICAL COMMUNICATIONS (2012)
Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes
Haibin Shi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
Lianne I. Willems et al.
ACCOUNTS OF CHEMICAL RESEARCH (2011)
Dynamic Monitoring of Newly Synthesized Proteomes: Up-Regulation of Myristoylated Protein Kinase A During Butyric Acid Induced Apoptosis
Kai Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe
Haibin Shi et al.
CHEMICAL COMMUNICATIONS (2011)
Activity-based probes: discovering new biology and new drug targets
William P. Heal et al.
CHEMICAL SOCIETY REVIEWS (2011)
Facing the gem-Dialkyl Effect in Enzyme Inhibitor Design: Preparation of Homocycloleucine-Based Azadipeptide Nitriles
Maxim Frizler et al.
CHEMISTRY-A EUROPEAN JOURNAL (2011)
Chemical Modification and Organelle-Specific Localization of Orlistat-Like Natural-Product-Based Probes
Peng-Yu Yang et al.
CHEMISTRY-AN ASIAN JOURNAL (2011)
Applying Small Molecule Microarrays and Resulting Affinity Probe Cocktails for Proteome Profiling of Mammalian Cell Lysates
Haibin Shi et al.
CHEMISTRY-AN ASIAN JOURNAL (2011)
High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome
Sam Alsford et al.
GENOME RESEARCH (2011)
Structural Optimization of Azadipeptide Nitriles Strongly Increases Association Rates and Allows the Development of Selective Cathepsin Inhibitors
Maxim Frizler et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
A Peptide Aldehyde Microarray for High-Throughput Profiling of Cellular Events
Hao Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)
Mingyu Hu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
The resurgence of covalent drugs
Juswinder Singh et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
One- and Two-Photon Live Cell Imaging Using a Mutant SNAP-Tag Protein and Its FRET Substrate Pairs
Chong-Jing Zhang et al.
ORGANIC LETTERS (2011)
Natural Products and Their Biological Targets: Proteomic and Metabolomic Labeling Strategies
Thomas Boettcher et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Antimalarial activity of azadipeptide nitriles
Reik Loeser et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Click synthesis of small molecule-peptide conjugates for organelle-specific delivery and inhibition of lysosomal cysteine proteases
Yuhui Loh et al.
CHEMICAL COMMUNICATIONS (2010)
Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections
Galina I. Lepesheva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy
Katrien Brak et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Novel Application of Electrostatic Repulsion-Hydrophilic Interaction Chromatography (ERLIC) in Shotgun Proteomics: Comprehensive Profiling of Rat Kidney Proteome
Piliang Hao et al.
JOURNAL OF PROTEOME RESEARCH (2010)
Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat - An FDA-Approved Drug with Anti-Tumor Activities
Peng-Yu Yang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Lipid metabolism in Trypanosoma brucei
Terry K. Smith et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2010)
Cathepsin L, target in cancer treatment?
Jacqueline M. Lankelma et al.
LIFE SCIENCES (2010)
The use of click chemistry in the emerging field of catalomics
Karunakaran A. Kalesh et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Crystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma brucei
Iain D. Kerr et al.
PLOS NEGLECTED TROPICAL DISEASES (2010)
Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole
Chiung-Kuang Chen et al.
PLOS NEGLECTED TROPICAL DISEASES (2010)
Functional Profiling, Identification, and Inhibition of Plasmepsins in Intraerythrocytic Malaria Parasites
Kai Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
Ellen M. Sletten et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design
Iain D. Kerr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania
Andrea Cavalli et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Kinetoplastid papain-like cysteine peptidases
Conor R. Caffrey et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2009)
Singapore Green: A New Fluorescent Dye for Microarray and Bioimaging Applications
Junqi Li et al.
ORGANIC LETTERS (2009)
Azadipeptide nitriles: Highly potent and proteolytically stable inhibitors of papain-like cysteine proteases
Reik Loeser et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Potency and selectivity of P2/P3-modified inhibitors of cysteine proteases from trypanosomes
Priyadarshini Jaishankar et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Activity-based protein profiling: New developments and directions in functional proteomics
Mahesh Uttamchandani et al.
CHEMBIOCHEM (2008)
Drugs targeting parasite lysosomes
Patricia S. Doyle et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
Activity-based probes as a tool for functional proteomic analysis of proteases
Marko Fonovic et al.
EXPERT REVIEW OF PROTEOMICS (2008)
A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition
Theresa C. O'Brien et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A Comparative Study of Electrostatic Repulsion-Hydrophilic Interaction Chromatography (ERLIC) versus SCX-IMAC-Based Methods for Phosphopeptide Isolation/Enrichment
Chee Sian Gan et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Identification of a new class of nonpeptidic inhibitors of cruzain
Katrien Brak et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Biogenesis of the trypanosome endo-exocytotic organelle is cytoskeleton mediated
Melanie Bonhivers et al.
PLOS BIOLOGY (2008)
RNA Interference of Trypanosoma brucei Cathepsin B and L Affects Disease Progression in a Mouse Model
Maha-Hamadien Abdulla et al.
PLOS NEGLECTED TROPICAL DISEASES (2008)
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing
Catherine X. Moss et al.
FEBS LETTERS (2007)
Target assessment for antiparasitic drug discovery
Julie A. Frearson et al.
TRENDS IN PARASITOLOGY (2007)
Sterol 14α-demethylase as a potential target for antitrypanosomal therapy:: Enzyme inhibition and parasite cell growth
Galina I. Lepesheva et al.
CHEMISTRY & BIOLOGY (2007)
A cysteine protease inhibitor cures Chagas' disease in an immunodeficient-mouse model of infection
Patricia S. Doyle et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Current concepts - Control of neglected tropical diseases
Peter J. Hotez et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Transfusion-acquired Trypanosoma cruzi infection
C. Young et al.
TRANSFUSION (2007)
Drug discovery and development for neglected parasitic diseases
Adam R. Renslo et al.
NATURE CHEMICAL BIOLOGY (2006)
Mechanism-based profiling of enzyme families
Michael J. Evans et al.
CHEMICAL REVIEWS (2006)
A cysteine protease inhibitor protects dogs from cardiac damage during infection by Trypanosoma cruzi
SC Barr et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Interaction of papain-like cysteine proteases with dipeptide-derived nitriles
R Löser et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Cathepsin L is involved in proteolytic processing of the Hendra virus fusion protein
CT Pager et al.
JOURNAL OF VIROLOGY (2005)
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
G Simmons et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
K Chandran et al.
SCIENCE (2005)
Characterization of two protein disulfide isomerases from the endocytic pathway of bloodstream forms of Trypanosoma brucei
J Rubotham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells
Toshiyuki Nomura et al.
JOURNAL OF MEDICAL INVESTIGATION (2005)
An activity-based probe for the determination of cysteine cathepsin protease activities in whole cells
JP Falgueyret et al.
ANALYTICAL BIOCHEMISTRY (2004)
A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei
ZB Mackey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Antimalarial activities of novel synthetic cysteine protease inhibitors
BJ Lee et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Irreversible inhibitors of serine, cysteine, and threonine proteases
JC Powers et al.
CHEMICAL REVIEWS (2002)
Cysteine proteases of parasitic organisms
M Sajid et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2002)
Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense
CR Caffrey et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2001)
A target within the target:: probing Cruzain's P1′ site to define structural determinants for the Chagas' disease protease
LS Brinen et al.
STRUCTURE WITH FOLDING & DESIGN (2000)
分享论文
