期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 18, 期 49, 页码 15816-15821出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201202672
关键词
alkenylation; amination; C-H activation; cyclization; palladium; phenanthridines
资金
- National Basic Research Program of China [2011CB936003]
- Natural Science Foundation of China [21072169]
A new protocol for the palladium-catalyzed free-amine-directed alkenylation of C(sp2)?H bonds and cycloamination is described. Substituted biaryl-2-amines react with various alkenes, including electron-deficient alkenes, aryl alkenes and alkyl alkenes, to give the corresponding phenanthridines with exclusive regioselectivity. The use of a-branched styrenes leads to the formation of tricyclic compounds with a seven-membered amine ring. The method operates through a free-amine-directed alkenylation and a subsequent hydroamination cyclization reaction.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据