期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 17, 期 5, 页码 1388-1408出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201001451
关键词
alkaloids; heterocycles; natural products; peptides
资金
- PharmaMar (Madrid), CICYT [CTQ2009-07758/BQU]
- Institut de Salud Carlos III [CB06_01_0074]
- Generalitat de Catalunya [2009SGR 1024]
- Institute for Research in Biomedicine
- Barcelona Science Park
Research on natural products containing hexahydropyrrolo[2,3-b]indole (HPI) has dramatically increased during the past few years. Newly discovered natural products with complex structures and important biological activities have recently been isolated and synthesized. This review summarizes the structures, biological activities, and synthetic routes for natural compounds containing HP1, emphasizing the different strategies for assembling this motif. It covers a broad range of molecules, from small alkaloids to complex peptides.
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