期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 16, 期 32, 页码 9890-9904出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201000471
关键词
asymmetry; conjugate addition; copper; Grignard reaction; N-heterocyclic carbenes
资金
- Swiss National Research Foundation [200020-126663]
- COST action D40 [C07 0097]
The copper-catalyzed conjugate addition of Grignard reagents to 3-substituted cyclic enones allows the formation of all-carbon chiral quaternary centers We demonstrate in this article that N-heterocyclic carbencs act as efficient chiral ligands for this transformation High enantioselectivities (up to 96% ee) could be obtained for a variety of substrates
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据