期刊
CHEMISTRY OF NATURAL COMPOUNDS
卷 50, 期 2, 页码 214-216出版社
SPRINGER
DOI: 10.1007/s10600-014-0915-y
关键词
dothiorelone; Dothiorella sp.; cytotoxicity
资金
- Natural Science Foundation of Fujian [2012J05058]
- Doctor Foundation of Jimei University [ZQ2011004]
- Li Shangda Subject Foundation of Jimei University [C2012006]
Two new polyketides, named dothiorelones F (2) and I (3), as well as three known analogues (dothiorelones E (1), G (4), and H (5)) have been isolated from the mangrove endophytic fungus Dothiorella sp. Their structures were elucidated on the basis of NMR data and mass spectrometry. Dothiorelones F (2) and G (4) showed significant cytotoxicity against Raji cancer cell line with IC50 values 2 mu g/mL.
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