HUMULENE AND ITS DERIVATIVES FROM Betula pendula BUDS

Humulene and its derivatives (6R)-hydroxy-alpha-humulene [(6R)-hydroxy-(1E, 4E, 8E)-4,8,11,11-tetramethylcycloundeca- 1,4,8-triene], (6R)-acetoxy-alpha-humulene [(6R)-acetoxy-(1E, 4E, 8E)-4,8,11,11-tetramethylcycloundeca- 1,4,8-triene], a coumaric acid ester, 14-hydroxy-alpha-humulene [14-coumaroxy-(1E, 4E, 8E)-4,8,11,11-tetramethylcycloundeca-1,4,8-triene], (1E, 6R, 8E)-4,5-epoxy-6-hydroxy-4,8,11,11-tetramethylcycloundeca- 1,8-diene, and (6R, 9S)-4,11,11-trimethyl-8-methylene-1,4-cycloundecadien-6,9-diol were observed in the hydrocarbon extract of Betula pendula (Betulaceae) buds. The GC retention indices were determined for all identified compounds.