Direct Assembly of Anisotropic Layered Double Hydroxide (LDH) Nanocrystals on Spherical Template for Fabrication of Drug-LDH Hollow Nanospheres

We report the direct assembly of anisotropic layered double hydroxide nanocrystals from a stable colloidal suspension onto spherical templates in a single step for the generation of hollow nanospheres. This approach does not involve the conventional wexfoliation/LBL-stacking process. LDH hollow nanospheres intercalated with drug anions are fabricated on the basis of the memory effect.