Synthesis of nitromethyl-, N-methylindolyl-, or N-methylindolyl-nitromethyl-substituted 1,4-benzothiazin(diazin)ones and 3-methyl-1,4-benzoxazinones from alkyl 3-nitroacrylates

The reactions of alkyl 3-nitroacrylates and ethyl 2-(1-methyl-1H-indol-3-yl)-3-nitroacrylate with o-aminothiophenol,o-aminophenol,o-phenylenediamine, and their substituted analogs were used for the preparation of 2-(nitromethyl)-2H-1,4-benzothiazin-3(4H)-one, 2-(1-methyl-1H-indol-3-yl)-2-(nitromethyl)-2H-1,4-benzothiazin-3(4H)-one, 3-methyl-2H-1,4-benzoxazin-2-ones, and 3-(1-methyl1H- indol-3-yl) quinoxalin-2(1H)-ones that were structurally characterized.