Synthesis of imidazo[4,5-e][1,3]thiazolo-[3,2-b][1,2,4]triazines

Perhydroimidazo[4,5-e][1,2,4]triazine-3-thiones are alkylated with bromoacetic acid to give previously unreported imidazo[4,5-e][1,3]thiazolo[3,2-b][1,2,4]triazines whose structure has been confirmed by X-ray structural analysis.