4.3 Article

Cyclopentane-condensed Chromones from Marine-derived Fungus Penicillium oxalicum

期刊

CHEMISTRY LETTERS
卷 43, 期 6, 页码 837-839

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CHEMICAL SOC JAPAN
DOI: 10.1246/cl.140138

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资金

  1. National Natural Science Foundation of China [41376160]
  2. National Marine Public Welfare Research Project of China [201305017]
  3. regional innovation demonstration project of Guangdong Province marine economic development [GD2012-D01-002]
  4. National Basic Research Program of China (973 Program) [2010CB833803]
  5. National High Technology Research and Development Program of China (863 Program) [2012AA092104]

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Five new cyclopentane-condensed chromones, coniochaetones G-K (1-5), along with four known compounds -penicillone C (6), penicillanone (7), conioxanthone A (8), and pinselin (9) were isolated from the crude extract of marine-derived fungus Penicillium oxalicum. The structures of 1-5 were elucidated by NMR, MS, ER, UV, and CD spectra. Metabolites 1-5 were evaluated for cytotoxicity, antibacterial, and antifouling activities.

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