Manganese Oxide-catalyzed Additive- and Solvent-free Aerobic Oxidative Synthesis of Primary Amides from Primary Amines

Various kinds of primary amides could be synthesized through indirect aerobic oxygenation of primary amines using simple amorphous MnO2 under additive- and solvent-free conditions. The catalyst/product separation was very easy, and the retrieved MnO2 catalyst could be reused without an appreciable loss of its high catalytic performance.