期刊
CHEMISTRY LETTERS
卷 41, 期 10, 页码 1223-1225出版社
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2012.1223
关键词
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资金
- Japan Society for the Promotion of Science (JSPS) [24681028, 20350080]
- Grants-in-Aid for Scientific Research [20350080, 24681028] Funding Source: KAKEN
We examined the thermal stability of organic inorganic hybrid bicelles, which are lipid bilayer nanodiscs encompassed by siloxane surfaces. The hybrid bicelles were formed with a binary lipid mixture consisting of a long-chain alkoxysilane lipid and a short-chain phospholipid. It was clarified that the hybrid bicelles maintained a discoid assembly in water beyond the temperature of the gel to liquid-crystalline phase transition of the face-forming long-chain lipid, at which conventional phospholipid bicelles are transformed spontaneously to vesicles.
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