Cross-coupling Reactions of Organoboranes: An Easy Method for C-C Bonding

The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides or triflates in the presence of base provides a powerful and general methodology for the formation of carbon-carbon bonds. The Csp(2)-B compounds (such as aryl- and 1-alkenylboron derivatives) and Csp(3)-B compounds (alkylboron compounds) readily cross-couple with organic electrophiles to give coupled products selectively in high yields. Recently, the Csp-B compounds (1-alkynylboron derivatives) have been also observed to react with organic electrophiles to produce expected cross-coupled products. The overview of some of such coupling reactions is discussed here in this article.