期刊
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
卷 22, 期 10, 页码 731-736出版社
WILEY
DOI: 10.1002/jhbp.268
关键词
Laparoscopic distal pancreatectomy; Morbidity; Pancreatic fistula; Propensity score-matching
资金
- Johnson Johnson
- Covidien Japan
- Taiho Pharmaceutical Company
- Chugai Pharmaceutical Company
- Pfizer
- Eli Lilly Japan
- Bristol Meyers Squib
- Otsuka Pharmaceutical Factory
- Takeda Pharmaceutical Company Ltd
- Eisai
- Yakult
- Daiichi Sankyo
- Mitsubishi
- Tanabe Pharma
- Merck
- Shionogi
Background Laparoscopic distal pancreatectomy has been shown to be associated with favorable postoperative outcomes using meta-analysis. However, there have been no randomized controlled studies yet. This study aimed to compare laparoscopic and open distal pancreatectomy using propensity score-matching. Methods We retrospectively collected perioperative data of 2,266 patients who underwent distal pancreatectomy in 69 institutes from 2006-2013 in Japan. Among them, 2,010 patients were enrolled in this study and divided into two groups, laparoscopic distal pancreatectomy and open distal pancreatectomy. Perioperative outcomes were compared between the groups using unmatched and propensity matched analysis. Results After propensity score-matching, laparoscopic distal pancreatectomy was associated with favorable perioperative outcomes compared with open distal pancreatectomy, including higher rate of preservation of spleen and splenic vessels (P<0.001); lower rates of intraoperative transfusion (P=0.020), clinical grade of pancreatic fistula (International Study Group on Pancreatic Fistula grade B and C; P<0.001), and morbidity (P<0.001); and shorter hospital stay (P=0.001), but a longer operative time (P<0.001). Conclusions Laparoscopic distal pancreatectomy was associated with more favorable perioperative outcomes than open distal pancreatectomy.
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