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Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance
William Matsui et al.
CANCER RESEARCH (2008)
Targeting cancer stem cells through L1CAM suppresses glioma growth
Shideng Bao et al.
CANCER RESEARCH (2008)
The erythropoietin receptor in normal and cancer tissues
Wolfgang Jelkmann et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2008)
Recent advances in cancer stem cells
Robert W. Cho et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)
L1-CAM in cancerous tissues
Nancy Gavert et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2008)
Plerixafor, a CXCR4 antagonist for the mobilization of hematopoietic stem cells
Geoffrey L. Uy et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2008)
Alemtuzumab in the treatment of chronic lymphocytic lymphoma
Kevin Boyd et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2008)
Prostate cancer stem cells: A new target for therapy
Norman J. Maitland et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3
A. Tzankov et al.
JOURNAL OF CLINICAL PATHOLOGY (2008)
Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas:: a randomised controlled trial (RICOVER-60)
Michael Pfreundschuh et al.
LANCET ONCOLOGY (2008)
CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL
Y. Kong et al.
LEUKEMIA (2008)
Identification of cells initiating human melanomas
Tobias Schatton et al.
NATURE (2008)
Efficient tumour formation by single human melanoma cells
Elsa Quintana et al.
NATURE (2008)
No place like home: anatomy and function of the stem cell niche
D. Leanne Jones et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Drug therapy: Monoclonal antibody therapy for B-cell non-Hodgkin's lymphoma
Bruce D. Cheson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
H. Korkaya et al.
ONCOGENE (2008)
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
L. Vermeulen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cytogenetic, molecular genetic, and clinical characteristics of acute myeloid leukemia with a complex karyotype
Krzysztof Mrozek
SEMINARS IN ONCOLOGY (2008)
Identification of a Small Subpopulation of Candidate Leukemia-Initiating Cells in the Side Population of Patients with Acute Myeloid Leukemia
Bijan Moshaver et al.
STEM CELLS (2008)
Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis
Costanza Bogani et al.
STEM CELLS (2008)
Diagnostic algorithms, monitoring, prognostication, and therapy in chronic myeloid leukemia (CML): a proposal of the Austrian CML platform
Peter Valent et al.
WIENER KLINISCHE WOCHENSCHRIFT (2008)
Aldehyde Dehydrogenase as a Marker for Stem Cells
Jan S. Moreb
CURRENT STEM CELL RESEARCH & THERAPY (2008)
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
S. Ma et al.
ONCOGENE (2008)
Identification and expansion of the tumorigenic lung cancer stem cell population
A. Eramo et al.
CELL DEATH AND DIFFERENTIATION (2008)
A functional Notch-survivin gene signature in basal breast cancer
Connie W. Lee et al.
BREAST CANCER RESEARCH (2008)
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes:: evidence from a core dataset of 2124 patients
Detlef Haase et al.
BLOOD (2007)
Iet-7 regulates self renewal and tumorigenicity of breast cancer cells
Fengyan Yu et al.
CELL (2007)
Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America
Donna M. Weber et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo
Christian Moser et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
Fumihiko Ishikawa et al.
NATURE BIOTECHNOLOGY (2007)
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
Christophe Ginestier et al.
CELL STEM CELL (2007)
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
NATURE (2007)
The novel AML stem cell-associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells
Anna van Rhenen et al.
BLOOD (2007)
CD44-positive colorectal adenoma cells express the potential stem cell markers musashi antigen (msi1) and ephrin B2 receptor (EphB2)
A. Schulenburg et al.
JOURNAL OF PATHOLOGY (2007)
Making a tumour's bed: glioblastoma stem cells and the vascular niche
Richard J. Gilbertson et al.
NATURE REVIEWS CANCER (2007)
Cancer stem cells in solid tumors
Laurie E. Ailles et al.
CURRENT OPINION IN BIOTECHNOLOGY (2007)
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
Patrick C. Hermann et al.
CELL STEM CELL (2007)
Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung
Yuanbin Chen et al.
CANCER RESEARCH (2007)
Expression and function of erythropoietin receptors in tumors - Implications for the use of erythropoiesis-stimulating agents in cancer patients
Angus M. Sinclair et al.
CANCER (2007)
Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1α and vascular endothelial growth factor A in bone marrow
Jean-Pierre Levesque et al.
STEM CELLS (2007)
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia
Naoki Hosen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Phenotypic characterization of human colorectal cancer stem cells
Piero Dalerba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells
C. Brendel et al.
LEUKEMIA (2007)
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada clinical trials group
Malcolm J. Moore et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Hypoxia-inducible factors, stem cells, and cancer
Brian Keith et al.
CELL (2007)
Activated intrinsic apoptosis pathway is a key related prognostic parameter in acute myeloid leukemia
Corine J. Hess et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
C. Pinto et al.
ANNALS OF ONCOLOGY (2007)
Identification of pancreatic cancer stem cells
Chenwei Li et al.
CANCER RESEARCH (2007)
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine A. O'Brien et al.
NATURE (2007)
Identification and expansion of human colon-cancer-initiating cells
Lucia Ricci-Vitiani et al.
NATURE (2007)
A perivascular niche for brain tumor stem cells
Christopher Calabrese et al.
CANCER CELL (2007)
Expression of the target receptor CD33 in CD34(+)/CD38(-)/CD123(+) AML stem cells
A. W. Hauswirth et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2007)
Selective targeting of cancer stem cells - A new concept in cancer therapeutics
Hasan Korkaya et al.
BIODRUGS (2007)
Primitive, quiescent and difficult to kill - The role of non-proliferating stem cells in chronic myeloid leukemia
David J. Barnes et al.
CELL CYCLE (2006)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells
Daniela S. Krause et al.
NATURE MEDICINE (2006)
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
Liqing Jin et al.
NATURE MEDICINE (2006)
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
Shideng Bao et al.
CANCER RESEARCH (2006)
Expression of β-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis
L. Ysebaert et al.
LEUKEMIA (2006)
Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial
Mats Brune et al.
BLOOD (2006)
The stem-cell niche as an entity of action
DT Scadden
NATURE (2006)
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
Suling Liu et al.
CANCER RESEARCH (2006)
BCR-ABL activity and its response to drugs can be determined in CD34+ CML stem cells by CrkL phosphorylation status using flow cytometry
A. Hamilton et al.
LEUKEMIA (2006)
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Omer H. Yilmaz et al.
NATURE (2006)
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Jiwang Zhang et al.
NATURE (2006)
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
CHM Jamieson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Roots and stems: stem cells in cancer
K Polyak et al.
NATURE MEDICINE (2006)
HIF-2α regulates Oct-4:: effects of hypoxia on stem cell function, embryonic development, and tumor growth
KL Covello et al.
GENES & DEVELOPMENT (2006)
Implications of the expression of myeloid markers on normal and leukemic stem cells
DJ Pearce et al.
CELL CYCLE (2006)
Detection of molecular targets on the surface of CD34+/CD38-stem cells in various myeloid malignancies
S Florian et al.
LEUKEMIA & LYMPHOMA (2006)
Chronic myelogenous leukemia (CML): resistance to tyrosine kinase inhibitors
A. Hochhaus
ANNALS OF ONCOLOGY (2006)
EGFR mutation in gefitinib-responsive small-cell lung cancer
I Okamoto et al.
ANNALS OF ONCOLOGY (2006)
Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia
DC Taussig et al.
BLOOD (2005)
Biology of normal and acute myeloid leukemia stem cells
JE Dick et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2005)
Hypoxia requires Notch signaling to maintain the undifferentiated cell state
MV Gustafsson et al.
DEVELOPMENTAL CELL (2005)
A tumorigenic subpopulation with stem cell properties in melanomas
D Fang et al.
CANCER RESEARCH (2005)
Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
HA Burris et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A north central cancer treatment group study
E Galanis et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases
TA Carter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis
VS Donnenberg et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
L Patrawala et al.
CANCER RESEARCH (2005)
Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival
J Kim et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice
S Tavor et al.
CANCER RESEARCH (2004)
A distinct side population of cells with high drug efflux capacity in human tumor cells
C Hirschmann-Jax et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
VEGF-R2 and neuropilin-1 are involved in VEGF-A-induced differentiation of human bone marrow progenitor cells
P Fons et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
Epithelial-mesenchymal transitions:: Twist in development and metastasis
YB Kang et al.
CELL (2004)
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
DJ Ceradini et al.
NATURE MEDICINE (2004)
Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas
B Streubel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Kit as a human oncogenic tyrosine kinase
Y Kitamura et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2004)
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
KJ Hope et al.
NATURE IMMUNOLOGY (2004)
Identification of human brain tumour initiating cells
SK Singh et al.
NATURE (2004)
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
Y Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cancerous stem cells can arise from pediatric brain tumors
HD Hemmati et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
B Löwenberg et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
G Dontu et al.
GENES & DEVELOPMENT (2003)
Prognostic significance of cytogenetic clonal evolution in patients with chronic myelogenous leukemia on imatinib mesylate therapy
JE Cortes et al.
BLOOD (2003)
Prospective identification of tumorigenic breast cancer cells
M Al-Hajj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Treatment of relapsed or refractory acute myeloid leukemia with humanized anti-D33 monoclonal antibody HuM195
E Feldman et al.
LEUKEMIA (2003)
Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
MA Bookman et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Rituximab - A review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia
GL Plosker et al.
DRUGS (2003)
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics:: a study of the AML Study Group Ulm
S Fröhling et al.
BLOOD (2002)
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)
RA Larson et al.
LEUKEMIA (2002)
Peripheral lymph node stromal cells can promote growth and tumorigenicity of breast carcinoma cells through the release of IGF-I and EGF
C LeBedis et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Spectrum of associated clonal hematologic non-mast cell lineage disorders occurring in patients with systemic mastocytosis
WR Sperr et al.
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2002)
Immature leukemic CD34(+)CXCR4(+) cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1
A Peled et al.
STEM CELLS (2002)
Stem cells, cancer, and cancer stem cells
T Reya et al.
NATURE (2001)
Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells
ML Guzman et al.
BLOOD (2001)
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
GG Wulf et al.
BLOOD (2001)
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
ME Gorre et al.
SCIENCE (2001)
Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3
TL Holyoake et al.
BLOOD (2001)
CD133 (AC133) expression on AML cells and progenitors
SM Vercauteren et al.
CYTOTHERAPY (2001)
The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells
CT Jordan et al.
LEUKEMIA (2000)
Biological effects of stroma-derived factor-1α on normal and CML CD34+ haemopoietic cells
J Dürig et al.
LEUKEMIA (2000)
Autonomous multi-lineage differentiation in vitro of primitive CD34+ cells from patients with chronic myeloid leukemia
X Jiang et al.
LEUKEMIA (2000)
Evidence from a leukaemia model for maintenance of vascular endothelium by bone-marrow-derived endothelial cells
E Gunsilius et al.
LANCET (2000)
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