4.5 Article

Vistriterpenoids A and B, Two New 24-Nor-oleanane Triterpenoids from Dodonaea viscosa

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CHEMISTRY & BIODIVERSITY
卷 15, 期 11, 页码 -

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201800426

关键词

Dodonaea viscosa; vistriterpenoids A and B; triterpenoids; protein tyrosine phosphatase 1b (PTP1B); PTP1B inhibitors; inhibitory activity

资金

  1. National Natural Science Foundation of China [21672040, 81222045]
  2. National Key Research and Development Program of China [2016YFC1305505]
  3. Shanghai Commission of Science and Technology [16JC1405000]

向作者/读者索取更多资源

Two new triterpenoids, vistriterpenoids A (1) and B (2), and four known ones, were acquired from Dodonaea viscosa. Compounds 1 and 2 represent the 24-nor-oleanane triterpenoids isolated from the genus Dodonaea for the first time. Their structures were identified based on extensive spectroscopic methods. Compounds 1, 2, 5, and 6 exerted inhibitory activities against PTP1B in vitro.

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