期刊
CHEMISTRY & BIODIVERSITY
卷 15, 期 11, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201800426
关键词
Dodonaea viscosa; vistriterpenoids A and B; triterpenoids; protein tyrosine phosphatase 1b (PTP1B); PTP1B inhibitors; inhibitory activity
资金
- National Natural Science Foundation of China [21672040, 81222045]
- National Key Research and Development Program of China [2016YFC1305505]
- Shanghai Commission of Science and Technology [16JC1405000]
Two new triterpenoids, vistriterpenoids A (1) and B (2), and four known ones, were acquired from Dodonaea viscosa. Compounds 1 and 2 represent the 24-nor-oleanane triterpenoids isolated from the genus Dodonaea for the first time. Their structures were identified based on extensive spectroscopic methods. Compounds 1, 2, 5, and 6 exerted inhibitory activities against PTP1B in vitro.
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