期刊
CHEMISTRY & BIODIVERSITY
卷 8, 期 3, 页码 467-475出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201000044
关键词
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资金
- University of Buenos Aires [X124]
- ANPCyT/FONCYT [PICT 34111]
- NIH [P41RR0954]
- National Research Council of Argentina (CONICET)
Two new triterpene glycosides, patagonicosides B and C (2 and 3, resp.), together with the known patagonicoside A (1), have been isolated from the EtOH extract of the sea cucumber Psolus patagonicus. The structures of the new compounds were established on the basis of extensive NMR spectroscopic analysis (1H- and C-13-NMR, H-1, H-1-COSY, HMBC, HSQC, TOCSY, and NOESY), HR-ESI-MS data, and chemical transformations. Compounds 1-3 and their desulfated analogs showed antifungal activities against the phytopathogenic fungus Cladosporium cladosporoides in a dose-dependent fashion.
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