期刊
CHEMISTRY & BIODIVERSITY
卷 6, 期 6, 页码 903-915出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.200800153
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The MeOH extract and its BuOH-soluble fraction (crude saponin fraction) from the flower buds of chinese tea plant (Camellia sinensis (L.) O. KUNTZE; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice and inhibitory effects against pancreatic lipase. From the BuOH-soluble fraction, three new acylated oleanane-type triterpene oligoglycosides, chakasaponins I, II, and III (1-3, resp), were isolated together with 13 known compound. The chemical structures 1-3 were elucidated on the basis of chemical and physicochemical evidence. Compounds 1-3 showed accelerating effects on gastrointestinal transit in mice and inhibitory effects against porcine pancreatic lipase (IC50 = 150 -530 mu M).
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