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ANALYTICAL CHEMISTRY (2014)
Ratiometric Two-Photon Fluorescent Probe for Quantitative Detection of β-Galactosidase Activity in Senescent Cells
Hyo Won Lee et al.
ANALYTICAL CHEMISTRY (2014)
In Vivo Imaging of Mouse Tumors by a Lipidated Cathepsin S Substrate
Hai-Yu Hu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Selective Ablation of β-Galactosidase-Expressing Cells with a Rationally Designed Activatable Photosensitizer
Yuki Ichikawa et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
In Vivo Imaging of Intraperitoneally Disseminated Tumors in Model Mice by Using Activatable Fluorescent Small-Molecular Probes for Activity of Cathepsins
Tomohiko Fujii et al.
BIOCONJUGATE CHEMISTRY (2014)
Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs
Lin Zhu et al.
BIOMATERIALS (2014)
Synthesis and evaluation of new NIR-fluorescent probes for cathepsin B: ICT versus FRET as a turn-ON mode-of-action
Einat Kisin-Finfer et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
A highly selective ratiometric fluorescent probe for in vitro monitoring and cellular imaging of human carboxylesterase 1
Zhao-Ming Liu et al.
BIOSENSORS & BIOELECTRONICS (2014)
Tagging Live Cells that Express Specific Peptidase Activity with Solid-State Fluorescence
Maxime Prost et al.
CHEMBIOCHEM (2014)
A furanyl acryl conjugated coumarin as an efficient inhibitor and a highly selective off-on fluorescent probe for covalent labelling of thioredoxin reductase
Lei Huang et al.
CHEMICAL COMMUNICATIONS (2014)
Double gating'' - a concept for enzyme-responsive imaging probes aiming at high tissue specificity
Maxime Prost et al.
CHEMICAL COMMUNICATIONS (2014)
Radiosensitization by erlotinib and veliparib in esophageal squamous cell cancer
Alexander Whitley et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Prodrug-Inspired Probes Selective to Cathepsin B over Other Cysteine Cathepsins
Morshed A. Chowdhury et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Highly Selective Off-On Fluorescent Probe for Imaging Thioredoxin Reductase in Living Cells
Liangwei Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides
Roy Weinstain et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Detection and Cellular Imaging of Human Cancer Enzyme Using a Turn-On, Wavelength-Shiftable, Self-Immolative Profluorophore
Suraj U. Hettiarachchi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Toward a Chemical Marker for Inflammatory Disease: A Fluorescent Probe for Membrane-Localized Thioredoxin
Min Hee Lee et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ
Youyong Yuan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo
Deju Ye et al.
NATURE CHEMISTRY (2014)
Strategies in the Design of Small-Molecule Fluorescent Probes for Peptidases
Laizhong Chen et al.
MEDICINAL RESEARCH REVIEWS (2014)
The regulatory roles of phosphatases in cancer
J. Stebbing et al.
ONCOGENE (2014)
Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling
Paulina Kasperkiewicz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease models
Lin Li et al.
NATURE COMMUNICATIONS (2014)
Fluorescent Light-up Probe with Aggregation-Induced Emission Characteristics for Alkaline Phosphatase Sensing and Activity Study
Jing Liang et al.
ACS APPLIED MATERIALS & INTERFACES (2013)
A novel near-infrared fluorescent probe for selectively sensing nitroreductase (NTR) in an aqueous medium
Youmin Shi et al.
ANALYST (2013)
A turn-on fluorescent probe for detection of tyrosinase activity
Changcheng Wang et al.
ANALYST (2013)
A new fluorometric turn-on assay for alkaline phosphatase and inhibitor screening based on aggregation and deaggregation of tetraphenylethylene molecules
Xinggui Gu et al.
ANALYST (2013)
Ratiometric Activatable Cell-Penetrating Peptides Provide Rapid In Vivo Readout of Thrombin Activation
Michael Whitney et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
A Switchable Two-Photon Membrane Tracer Capable of Imaging Membrane-Associated Protein Tyrosine Phosphatase Activities
Lin Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Development of Azo-Based Fluorescent Probes to Detect Different Levels of Hypoxia
Wen Piao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides
Elamprakash N. Savariar et al.
CANCER RESEARCH (2013)
7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off-on probe for highly sensitive and selective detection of nitroreductase
Zhao Li et al.
CHEMICAL COMMUNICATIONS (2013)
A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: selective detection and quantification
Ting Guo et al.
CHEMICAL COMMUNICATIONS (2013)
High selectivity imaging of nitroreductase using a near-infrared fluorescence probe in hypoxic tumor
Kehua Xu et al.
CHEMICAL COMMUNICATIONS (2013)
Energy transfer cassettes based on organic fluorophores: construction and applications in ratiometric sensing
Jiangli Fan et al.
CHEMICAL SOCIETY REVIEWS (2013)
Profluorogenic Reductase Substrate for Rapid, Selective, and Sensitive Visualization and Detection of Human Cancer Cells that Overexpress NQO1
William C. Silvers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Rational Design of Highly Sensitive Fluorescence Probes for Protease and Glycosidase Based on Precisely Controlled Spirocyclization
Masayo Sakabe et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Improved Quenched Fluorescent Probe for Imaging of Cysteine Cathepsin Activity
Martijn Verdoes et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Fluorescence Discrimination of Cancer from Inflammation by Molecular Response to COX-2 Enzymes
Hua Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
An Off-On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells
Hua Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS
Nan Li et al.
NATURE PROTOCOLS (2013)
Fluorescent light-up probe with aggregation-induced emission characteristics for in vivo imaging of cell apoptosis
Haibin Shi et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2013)
The first ratiometric fluorescent probes for aminopeptidase N cell imaging
Laizhong Chen et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2013)
Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety
Lin Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Fluorescence triggered by ligand-protein hydrophobic interaction
Liu ZhenZhen et al.
SCIENCE CHINA-CHEMISTRY (2013)
Keeping Bone Where Bone Belongs (vol 6, er10, 2013)
Leslie K. Ferrarelli
SCIENCE SIGNALING (2013)
Fluorescence-guided surgery with live molecular navigation - a new cutting edge
Quyen T. Nguyen et al.
NATURE REVIEWS CANCER (2013)
Upconversion Fluorescence Resonance Energy Transfer Based Biosensor for Ultrasensitive Detection of Matrix Metalloproteinase-2 in Blood
Yuhui Wang et al.
ANALYTICAL CHEMISTRY (2012)
Near-Infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold
Daihi Oushiki et al.
ANALYTICAL CHEMISTRY (2012)
Spatially Resolved Monitoring of Neutrophil Elastase Activity with Ratiometric Fluorescent Reporters
Stefanie Gehrig et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
An Inhibitor of Glutathione S-Transferase Omega 1 that Selectively Targets Apoptotic Cells
Nicholas J. Pace et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Detection of ubiquitin-proteasome enzymatic activities in cells: Application of activity-based probes to inhibitor development
Holger B. Kramer et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Activatable Near-Infrared Fluorescent Probe for In Vivo Imaging of Fibroblast Activation Protein-alpha
Jinbo Li et al.
BIOCONJUGATE CHEMISTRY (2012)
Detection of MMP-2 and MMP-9 Activity in Vivo with a Triple-Helical Peptide Optical Probe
Walter J. Akers et al.
BIOCONJUGATE CHEMISTRY (2012)
2-Nitroimidazole-Tricarbocyanine Conjugate as a Near-Infrared Fluorescent Probe for in Vivo Imaging of Tumor Hypoxia
Kensuke Okuda et al.
BIOCONJUGATE CHEMISTRY (2012)
Biological markers in osteoarthritis
J. Ch. Rousseau et al.
BONE (2012)
A robust, high-sensitivity stealth probe for peptidases
Oliver Thorn-Seshold et al.
CHEMICAL COMMUNICATIONS (2012)
Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity
Dokyoung Kim et al.
CHEMICAL COMMUNICATIONS (2012)
A Nonpeptidic Cathepsin S Activity-Based Probe for Noninvasive Optical Imaging of Tumor-Associated Macrophages
Martijn Verdoes et al.
CHEMISTRY & BIOLOGY (2012)
An Optimized Activity-Based Probe for the Study of Caspase-6 Activation
Laura E. Edgington et al.
CHEMISTRY & BIOLOGY (2012)
A Two-photon Fluorescent Probe for Intracellular Detection of Tyrosinase Activity
Shengyong Yan et al.
CHEMISTRY-AN ASIAN JOURNAL (2012)
Novel live imaging techniques of cellular functions and in vivo tumors based on precise design of small molecule-based 'Activatable' fluorescence probes
Yasuteru Urano
CURRENT OPINION IN CHEMICAL BIOLOGY (2012)
Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling
Dong Dong et al.
DRUG METABOLISM REVIEWS (2012)
The human phosphatase interactome: An intricate family portrait
Francesca Sacco et al.
FEBS LETTERS (2012)
Organelle-Specific Detection of Phosphatase Activities with Two-Photon Fluorogenic Probes in Cells and Tissues
Lin Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Mitochondrial Thioredoxin-Responding Off-On Fluorescent Probe
Min Hee Lee et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
An Activity-Based Near-Infrared Glucuronide Trapping Probe for Imaging β-Glucuronidase Expression in Deep Tissues
Ta-Chun Cheng et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Design Strategy for a Near-Infrared Fluorescence Probe for Matrix Metalloproteinase Utilizing Highly Cell Permeable Boron Dipyrromethene
Takuya Myochin et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Real-Time Monitoring of Cell Apoptosis and Drug Screening Using Fluorescent Light-Up Probe with Aggregation-Induced Emission Characteristics
Haibin Shi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
New approaches for dissecting protease functions to improve probe development and drug discovery
Edgar Deu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
LacZ β-galactosidase: Structure and function of an enzyme of historical and molecular biological importance
Douglas H. Juers et al.
PROTEIN SCIENCE (2012)
Imaging proteins inside cells with fluorescent tags
Georgeta Crivat et al.
TRENDS IN BIOTECHNOLOGY (2012)
Simultaneous Intracellular β-D-Glucosidase and Phosphodiesterase I Activities Measurements Based on A Triple-Signaling Fluorescent Probe
Yinhui Li et al.
ANALYTICAL CHEMISTRY (2011)
Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis
C. Mahendra Kumar et al.
BIOCHIMIE (2011)
Small-molecule probe using dual signals to monitor leucine aminopeptidase activity
Hey Young Yoon et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Caspases and cancer
M. Olsson et al.
CELL DEATH AND DIFFERENTIATION (2011)
A fluorescent turn-on probe for the detection of alkaline phosphatase activity in living cells
Tae-Il Kim et al.
CHEMICAL COMMUNICATIONS (2011)
Visualization of tyrosinase activity in melanoma cells by a BODIPY-based fluorescent probe
Tae-Il Kim et al.
CHEMICAL COMMUNICATIONS (2011)
Strategies for in vivo imaging of enzyme activity: an overview and recent advances
Andrew Razgulin et al.
CHEMICAL SOCIETY REVIEWS (2011)
Aggregation-induced emission
Yuning Hong et al.
CHEMICAL SOCIETY REVIEWS (2011)
Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes
Laura E. Edgington et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)
Mingyu Hu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
β-Galactosidase Fluorescence Probe with Improved Cellular Accumulation Based on a Spirocyclized Rhodol Scaffold
Mako Kamiya et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Molecular imaging of Cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe
Wael R. Abd-Elgaliel et al.
MOLECULAR BIOSYSTEMS (2011)
Tumor Hypoxia Imaging
Xilin Sun et al.
MOLECULAR IMAGING AND BIOLOGY (2011)
In Vivo Optical Imaging of Membrane-Type Matrix Metalloproteinase (MT-MMP) Activity
Lei Zhu et al.
MOLECULAR PHARMACEUTICS (2011)
A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell
Lei Cui et al.
ORGANIC LETTERS (2011)
Rapid Cancer Detection by Topically Spraying a γ-Glutamyltranspeptidase-Activated Fluorescent Probe
Yasuteru Urano et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Real-Time Video Imaging of Protease Expression In Vivo
Lei Zhu et al.
THERANOSTICS (2011)
Targeting hypoxia in cancer therapy
William R. Wilson et al.
NATURE REVIEWS CANCER (2011)
The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins
Oliver Rocks et al.
CELL (2010)
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kai Kessenbrock et al.
CELL (2010)
A near-infrared fluorescent probe for monitoring tyrosinase activity
Xiaohua Li et al.
CHEMICAL COMMUNICATIONS (2010)
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
Hisataka Kobayashi et al.
CHEMICAL REVIEWS (2010)
An Autoimmolative Spacer Allows First-Time Incorporation of a Unique Solid-State Fluorophore into a Detection Probe for Acyl Hydrolases
Xiao-bing Zhang et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Molecular imaging: current status and emerging strategies
M. A. Pysz et al.
CLINICAL RADIOLOGY (2010)
Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases
Benedicte Cauwe et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
Strategies for discovering and derisking covalent, irreversible enzyme inhibitors
Douglas S. Johnson et al.
FUTURE MEDICINAL CHEMISTRY (2010)
Specialized roles for cysteine cathepsins in health and disease
Jochen Reiser et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Hypoxia-Sensitive Fluorescent Probes for in Vivo Real-Time Fluorescence Imaging of Acute Ischemia
Kazuki Kiyose et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Fibroblast-activation protein: a single marker that confidently differentiates morpheaform/infiltrative basal cell carcinoma from desmoplastic trichoepithelioma
Ossama Abbas et al.
MODERN PATHOLOGY (2010)
A panel of subunit-selective activity-based proteasome probes
Martijn Verdoes et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
Quyen T. Nguyen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Dual-Function Probe to Detect Protease Activity for Fluorescence Measurement and F-19 MRI
Shin Mizukami et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared Fluorescent Peptide for Apoptosis Imaging
Dustin Maxwell et al.
BIOCONJUGATE CHEMISTRY (2009)
DUBs and cancer The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors
Sajjad Hussain et al.
CELL CYCLE (2009)
Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides
Todd A. Aguilera et al.
INTEGRATIVE BIOLOGY (2009)
Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe
Hyeran Lee et al.
JOURNAL OF BIOMEDICAL OPTICS (2009)
Design and Development of Enzymatically Activatable Photosensitizer Based on Unique Characteristics of Thiazole Orange
Yuichiro Koide et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Protein acyl thioesterases (Review)
Ruth Zeidman et al.
MOLECULAR MEMBRANE BIOLOGY (2009)
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation
Amanda Cobos-Correa et al.
NATURE CHEMICAL BIOLOGY (2009)
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes
Laura E. Edgington et al.
NATURE MEDICINE (2009)
Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model
Edward M. Barnett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Selective activity-based probes for cysteine cathepsins
Anja Watzke et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Dark quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis development in vivo
Seulki Lee et al.
BIOCONJUGATE CHEMISTRY (2008)
Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors
Xu Qiu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Affinity labeling of the proteasome by a belactosin A derived inhibitor
Makoto Hasegawa et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Imaging matrix metalloproteinases in cancer
Randy L. Scherer et al.
CANCER AND METASTASIS REVIEWS (2008)
Lanthanide-Based Protease Activity Sensors for Time-Resolved Fluorescence Measurements
Shin Mizukami et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Ras oncogenes: split personalities
Antoine E. Karnoub et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Enzyme Function Discovery
Debra Dunaway-Mariano
STRUCTURE (2008)
Mechanisms, biology and inhibitors of deubiquitinating enzymes
Kerry Routenberg Love et al.
NATURE CHEMICAL BIOLOGY (2007)
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
Galia Blum et al.
NATURE CHEMICAL BIOLOGY (2007)
Selective fluorescence probes for dipeptidyl peptidase activity - Fibroblast activation protein and dipeptidyl peptidase IV
Koon Siew Lai et al.
BIOCONJUGATE CHEMISTRY (2007)
Targeting enzyme inhibitors in drug discovery
Robert A. Copeland et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2
Stefaan Sansen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor
Farouc A. Jaffer et al.
CIRCULATION (2007)
Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
Kristin E. Bullok et al.
BIOCHEMISTRY (2007)
Melanocyte biology and skin pigmentation
Jennifer Y. Lin et al.
NATURE (2007)
Genomic structure and transcriptional regulation of the rat, mouse, and human carboxylesterase genes
Masakiyo Hosokawa et al.
DRUG METABOLISM REVIEWS (2007)
Caspase function in programmed cell death
S. Kumar
CELL DEATH AND DIFFERENTIATION (2007)
Design and synthesis of an enzyme activity-based labeling molecule with fluorescence spectral change
Toru Komatsu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Leucine aminopeptidases: diversity in structure and function
Mikiko Matsui et al.
BIOLOGICAL CHEMISTRY (2006)
Targeting tumor-associated carbonic anhydrase IX in cancer therapy
Anne Thiry et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Cysteine cathepsins: multifunctional enzymes in cancer
Mona Mostafa Mohamed et al.
NATURE REVIEWS CANCER (2006)
Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate
NH Ho et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities
Y Choe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The therapeutic potential of monoamine oxidase inhibitors
MBH Youdim et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Protein-tyrosine phosphatases and cancer
A Östman et al.
NATURE REVIEWS CANCER (2006)
Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging
K Kim et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
A novel role for placental leucine aminopeptidase (P-LAP) as a determinant of chemoresistance in endometrial carcinoma cells
C Kondo et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Expression of γ-glutamyltransferase in cancer cells and its significance in drug resistance
A Pompella et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Dynamic imaging of protease activity with fluorescently quenched activity-based probes
G Blum et al.
NATURE CHEMICAL BIOLOGY (2005)
Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib
CR Berkers et al.
NATURE METHODS (2005)
Design of optical switches as metabolic indicators: New fluorogenic probes for monoamine oxidases (MAO A and B)
G Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Methionine sulfoxide reductases: history and cellular role in protecting against oxidative damage
H Weissbach et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)
Profiling enzyme activities in vivo using click chemistry methods
AE Speers et al.
CHEMISTRY & BIOLOGY (2004)
In vivo imaging of β-galactosidase activity using far red fluorescent switch
CH Tung et al.
CANCER RESEARCH (2004)
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe
SM Messerli et al.
NEOPLASIA (2004)
Ligand selectivity and competition between enzymes in silico
A Macchiarulo et al.
NATURE BIOTECHNOLOGY (2004)
Enantioselective biocatalysis optimized by directed evolution
KE Jaeger et al.
CURRENT OPINION IN BIOTECHNOLOGY (2004)
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
T Jiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
DT-diaphorase: a target for new anticancer drugs
S Danson et al.
CANCER TREATMENT REVIEWS (2004)
Monoamine oxidase expression during development and aging
A Nicotra et al.
NEUROTOXICOLOGY (2004)
Caspase activation: Revisiting the induced proximity model
YG Shi
CELL (2004)
Molecular mechanisms of caspase regulation during apoptosis
SJ Riedl et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Human carboxylesterase 1: from drug metabolism to drug discovery
MR Redinbo et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2003)
An IFN-γ-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
T Saric et al.
NATURE IMMUNOLOGY (2002)
Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors
AS Kalgutkar et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2001)
Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme
T Sandalova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
In vivo molecular target assessment of matrix metalloproteinase inhibition
C Bremer et al.
NATURE MEDICINE (2001)
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools
D Greenbaum et al.
CHEMISTRY & BIOLOGY (2000)
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