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Synthetic approaches to monofluoroalkenes

期刊

CHEMICAL SOCIETY REVIEWS
卷 40, 期 5, 页码 2867-2908

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cs00201a

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资金

  1. Canada Research Chair Program
  2. Natural Sciences and Engineering Research Council of Canada
  3. Fonds de recherche sur la nature et les technologies (FQRNT)
  4. FQRNT Centre in Green Chemistry and Catalysis
  5. Merck Frosst Centre for Therapeutic Research
  6. Universite Laval

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Monofluoroalkenes are an important fluorinated class of compounds with applications in medicinal chemistry, material sciences and organic chemistry. An overview of methods allowing synthetic access to these fluorinated building blocks is provided. In particular, this critical review, which covers publications up to October 2010, will be divided according to the substitution pattern of the monofluoroalkenes, i.e. di-, tri- or tetra-substituted. Within each group, the various synthetic approaches will be divided according to the reaction type (282 references).

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